Hs06580399_cn

• Gene Symbol: SMYD2
• Assay Reference Genome Location: Chr.1:214310200 on build GRCh38
• Cytoband: 1q32.3

Target Gene Details

• Entrez Gene ID: 56950
• Gene Name: SET and MYND domain containing 2
• Gene Aliases: HSKM-B, KMT3C, ZMYND14
• Location: Chr.1:214281101-214337134 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SMYD2	NM_020197.2			NP_064582.2
	AF226053.1			AAF86953.1
	AK313868.1
	BC028104.1
	BC098133.1			AAH98133.1
	BC098276.1			AAH98276.1
	BC098335.1			AAH98335.1
	BG723585.1

More Information

Additional Information:

For this assay, SNP(s) [rs138771753] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
heart development
negative regulation of cell proliferation
histone H3-K36 methylation
peptidyl-lysine monomethylation
peptidyl-lysine dimethylation
regulation of DNA damage response, signal transduction by p53 class mediator
regulation of signal transduction by p53 class mediator

Function(s)

RNA polymerase II core binding
p53 binding
protein binding
lysine N-methyltransferase activity
protein-lysine N-methyltransferase activity
histone-lysine N-methyltransferase activity
metal ion binding
histone methyltransferase activity (H3-K36 specific)