Hs06490361_cn

• Gene Symbol: MBP
• Assay Reference Genome Location: Chr.18:76994172 on build GRCh38
• Cytoband: 18q23

Target Gene Details

• Entrez Gene ID: 4155
• Gene Name: myelin basic protein
• Gene Aliases: -
• Location: Chr.18:76978833-77133708 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MBP	NM_001025081.1			NP_001020252.1
	NM_001025090.1			NP_001020261.1
	NM_001025092.1			NP_001020263.1
	NM_001025101.1			NP_001020272.1
	NM_002385.2			NP_002376.1
	XM_011526009.2			XP_011524311.1
	AK098402.1
	AK128770.1
	AK128788.1
	AK289893.1
	AK293922.1
	AK296492.1
	AK314553.1
	BC008749.2
	BC080654.1			AAH80654.1
	BC101771.1
	BC101773.1
	BC143348.1
	BC143350.1
	BG766942.1
	CB153535.1
	CB156561.1
	CR536534.1			CAG38771.1
	CR541919.1			CAG46717.1
	CR627018.1			CAH10359.1
	M13577.1			AAA59562.1
	M30047.1			AAA59559.1
	M30515.1			AAA59564.1
	M30516.1			AAA59563.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2717388	Chr.18:76288671 - 78160297 on Build GRCh38	Deletion	MBP C18orf65 LINC00908 ZNF516 LOC400661 ZNF236 GALR1 LOC107987260 LINC00683 LOC100131655 LOC101927989 LINC01029 LOC101927651
esv3643197	Chr.18:76911767 - 77002929 on Build GRCh38	Loss	MBP ZNF236
nsv1063632	Chr.18:76317786 - 77170410 on Build GRCh38	Gain	MBP C18orf65 LINC00908 ZNF236 LOC107987260 ZNF516 LINC00683 LOC100131655 LOC101927989 LOC400661 LOC101927651

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

myelin protein, structural protein

Gene Ontology Categories:

Process(es)

immune response
chemical synaptic transmission
central nervous system development
aging
axon ensheathment
response to toxic substance
substantia nigra development
response to progesterone
response to tumor necrosis factor
myelination
response to mercury ion
negative regulation of axonogenesis
membrane organization
response to fatty acid

Function(s)

protease binding
protein binding
structural constituent of myelin sheath