Hs06347655_cn

• Gene Symbol: KLRG1
• Assay Reference Genome Location: Chr.12:9168498 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10219
• Gene Name: killer cell lectin like receptor G1
• Gene Aliases: 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
• Location: Chr.12:8989079-9255692 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRG1	XM_017018685.1			XP_016874174.1

Target Gene Details

• Entrez Gene ID: 5858
• Gene Name: PZP, alpha-2-macroglobulin like
• Gene Aliases: CPAMD6
• Location: Chr.12:9140730-9208370 on Build GRCh38
• Assay Gene Location: Within Intron 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PZP	NM_002864.2			NP_002855.2
	XM_011520804.2			XP_011519106.1
	XM_011520805.2			XP_011519107.1
	XM_011520806.1			XP_011519108.1
	XM_011520807.2			XP_011519109.1
	XM_017019763.1			XP_016875252.1
	XM_017019764.1			XP_016875253.1
	XM_017019765.1			XP_016875254.1
	XM_017019766.1			XP_016875255.1
	XM_017019767.1			XP_016875256.1
	AK308724.1
	AK313639.1
	BC111756.1			AAI11757.1
	X54380.1			CAA38255.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv523958	Chr.12:9150844 - 9396476 on Build GRCh38	Loss	KLRG1 A2MP1 LOC101928030 LINC00987 LOC642846 LOC105369649 LOC101930452 PZP MIR1244-3
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	LOC101928030 A2ML1 PHC1 CLEC4D KLRF1 DDX12P MFAP5 PZP KLRF2 AICDA CLEC2D CLEC2B RIMKLB CLEC2A LOC374443 CLEC6A LOC101930452 MIR1244-3 M6PR A2MP1 LINC00987 LINC00612 LOC105376678 OVOS LOC400002 LOC105369649 LOC728715 CLECL1 KLRG1 CLEC4E LOC642846 LOC105369728 CLEC12A LOC100506159 A2M-AS1 A2M KLRB1 CD69
nsv527404	Chr.12:9098005 - 9282648 on Build GRCh38	Gain	KLRG1 A2MP1 LINC00987 A2M PZP MIR1244-3
nsv557355	Chr.12:9157399 - 9376419 on Build GRCh38	Gain	KLRG1 A2MP1 LOC101928030 LINC00987 LOC642846 LOC105369649 LOC101930452 PZP MIR1244-3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor, protease inhibitor

Gene Ontology Categories:

Process(es)

inflammatory response
cellular defense response
cell surface receptor signaling pathway
innate immune response
female pregnancy
negative regulation of endopeptidase activity

Function(s)

receptor activity
protein binding
carbohydrate binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity