Hs06197363_cn

• Gene Symbol: CHMP4C
• Assay Reference Genome Location: Chr.8:81737433 on build GRCh38
• Cytoband: 8q21.13

Target Gene Details

• Entrez Gene ID: 92421
• Gene Name: charged multivesicular body protein 4C
• Gene Aliases: SNF7-3, Shax3, VPS32C
• Location: Chr.8:81732453-81759515 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHMP4C	NM_152284.3			NP_689497.1
	AB120734.1			BAC87888.1
	AK000049.1
	AK314873.1
	AY329086.1			AAQ91195.1
	BC014321.1			AAH14321.1
	BX492886.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv611607	Chr.8:81405621 - 81768032 on Build GRCh38	Gain	SLC10A5 PMP2 FABP12 ZFAND1 FABP9 FABP4 CHMP4C IMPA1
nsv831369	Chr.8:81605833 - 81823586 on Build GRCh38	Gain+Loss	SLC10A5 ZFAND1 CHMP4C SNX16 IMPA1

More Information

Additional Information:

For this assay, SNP(s) [rs73694770] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

cell separation after cytokinesis
autophagy
nucleus organization
mitotic metaphase plate congression
abscission
regulation of centrosome duplication
protein transport
endosomal transport
viral life cycle
negative regulation of cytokinesis
multivesicular body assembly
viral budding via host ESCRT complex
regulation of viral process
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
regulation of mitotic spindle assembly
positive regulation of viral release from host cell

Function(s)

protein binding
protein homodimerization activity