Hs06186672_cn

• Gene Symbol: LOC100507156
• Assay Reference Genome Location: Chr.8:23339506 on build GRCh38
• Cytoband: 8p21.3

Target Gene Details

• Entrez Gene ID: 100507156
• Gene Name: uncharacterized LOC100507156
• Gene Aliases: -
• Location: Chr.8:23336208-23366125 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC100507156	NR_038323.1
	AL833246.1

Target Gene Details

• Entrez Gene ID: 4017
• Gene Name: lysyl oxidase like 2
• Gene Aliases: LOR2, WS9-14
• Location: Chr.8:23296897-23404209 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOXL2	NM_002318.2			NP_002309.1
	AF117949.1			AAD34343.1
	AK222477.1			BAD96197.1
	AK293292.1
	AK312266.1
	BC000594.2			AAH00594.1
	KF928961.1
	KF975332.1
	U89942.1			AAB49697.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv7139n100	Chr.8:23292116 - 23464357 on Build GRCh38	Loss	R3HCC1 LOC100507156 ENTPD4 LOXL2
nsv610778	Chr.8:23316078 - 23341917 on Build GRCh38	Loss	LOC100507156 LOXL2
nsv1026345	Chr.8:23302920 - 23541056 on Build GRCh38	Gain	LOC100507156 SLC25A37 ENTPD4 LOXL2
nsv1017570	Chr.8:22969562 - 23544783 on Build GRCh38	Gain	LOC100507156 TNFRSF10D TNFRSF10C RHOBTB2 TNFRSF10B ENTPD4 R3HCC1 LOC286059 CHMP7 LOC254896 SLC25A37 LOC389641 TNFRSF10A LOC107984124 LOXL2

More Information

Additional Information:

For this assay, SNP(s) [rs74683574,rs80351317] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

response to hypoxia
epithelial to mesenchymal transition
endothelial cell proliferation
sprouting angiogenesis
transcription, DNA-templated
cellular protein modification process
receptor-mediated endocytosis
cell adhesion
aging
histone modification
protein deamination
collagen fibril organization
positive regulation of chondrocyte differentiation
endothelial cell migration
negative regulation of transcription, DNA-templated
response to copper ion
oxidation-reduction process

Function(s)

chromatin binding
transcription corepressor activity
protein-lysine 6-oxidase activity
scavenger receptor activity
copper ion binding
protein binding
electron carrier activity
methylated histone binding
oligosaccharide binding