Hs05735576_cn

• Gene Symbol: AIM2
• Assay Reference Genome Location: Chr.1:159065496 on build GRCh38
• Cytoband: 1q23.1

Target Gene Details

• Entrez Gene ID: 9447
• Gene Name: absent in melanoma 2
• Gene Aliases: PYHIN4
• Location: Chr.1:159059226-159132351 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AIM2	NM_004833.1			NP_004824.1
	XM_005245616.4			XP_005245673.1
	XM_017002848.1			XP_016858337.1
	AF024714.1			AAB81613.1
	AK292042.1
	BC010940.1			AAH10940.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv946445	Chr.1:159065253 - 159066111 on Build GRCh38	Duplication	AIM2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

activation of innate immune response
positive regulation of defense response to virus by host
apoptotic process
inflammatory response
immune response
negative regulation of NF-kappaB transcription factor activity
positive regulation of protein oligomerization
positive regulation of interleukin-1 beta production
tumor necrosis factor-mediated signaling pathway
cellular response to interferon-beta
cellular response to drug
innate immune response
interleukin-1 beta secretion
positive regulation of interleukin-1 beta secretion
positive regulation of NF-kappaB transcription factor activity
pyroptosis
positive regulation of cysteine-type endopeptidase activity

Function(s)

double-stranded DNA binding
protein binding
identical protein binding