Hs05580016_cn

• Gene Symbol: POLR2F
• Assay Reference Genome Location: Chr.22:37974891 on build GRCh38
• Cytoband: 22q13.1

Target Gene Details

• Entrez Gene ID: 5435
• Gene Name: RNA polymerase II subunit F
• Gene Aliases: HRBP14.4, POLRF, RPABC14.4, RPABC2, RPB14.4, RPB6, RPC15
• Location: Chr.22:37953663-38041915 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR2F	NM_001301130.1			NP_001288059.1
	NM_001301131.1			NP_001288060.1
	XM_017028832.1			XP_016884321.1
	AK094034.1
	BP195499.1
	DN989996.1

Target Gene Details

• Entrez Gene ID: 6663
• Gene Name: SRY-box 10
• Gene Aliases: DOM, PCWH, WS2E, WS4, WS4C
• Location: Chr.22:37972312-37984532 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SOX10	NM_006941.3			NP_008872.1
	AJ001183.1			CAA04576.1
	AK300945.1
	BC002824.2			AAH02824.1
	BC007595.1			AAH07595.1
	BT020029.1			AAV38832.1
	CR456584.1			CAG30470.1
	CR536571.1			CAG38808.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase

Gene Ontology Categories:

Process(es)

mRNA splicing, via spliceosome
transcription-coupled nucleotide-excision repair
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
transcription from RNA polymerase III promoter
fibroblast growth factor receptor signaling pathway
gene expression
gene silencing by RNA
positive regulation of type I interferon production
somatic stem cell population maintenance
snRNA transcription from RNA polymerase II promoter
positive regulation of gene expression, epigenetic
positive regulation of viral transcription
in utero embryonic development
neural crest cell migration
positive regulation of neuroblast proliferation
regulation of transcription from RNA polymerase II promoter
peripheral nervous system development
anatomical structure morphogenesis
positive regulation of gliogenesis
melanocyte differentiation
lacrimal gland development
negative regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
enteric nervous system development
digestive tract morphogenesis
developmental growth
oligodendrocyte differentiation
stem cell differentiation
morphogenesis of a branching epithelium
negative regulation of canonical Wnt signaling pathway

Function(s)

RNA polymerase I activity
RNA polymerase II activity
RNA polymerase III activity
DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription factor binding
chromatin binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
protein binding
transcription factor binding
identical protein binding