Hs05481548_cn

• Gene Symbol: PPM1E
• Assay Reference Genome Location: Chr.17:58764977 on build GRCh38
• Cytoband: 17q22

Target Gene Details

• Entrez Gene ID: 22843
• Gene Name: protein phosphatase, Mg2+/Mn2+ dependent 1E
• Gene Aliases: CaMKP-N, POPX1, PP2CH, caMKN
• Location: Chr.17:58755869-58985617 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPM1E	NM_014906.4			NP_055721.3
	NR_048561.1
	AB028995.1
	AF260269.1			AAF70325.1
	AF520614.1			AAM76058.1
	AK289966.1
	BC136290.1
	BC151228.1
	CR749253.1			CAH18109.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1057312	Chr.17:58748383 - 58804942 on Build GRCh38	Gain	PPM1E
nsv833498	Chr.17:58652063 - 58815031 on Build GRCh38	Loss	RAD51C PPM1E TEX14

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

negative regulation of protein kinase activity
cellular response to drug
peptidyl-threonine dephosphorylation
positive regulation of stress fiber assembly

Function(s)

protein serine/threonine phosphatase activity
protein binding
metal ion binding