Hs05355500_cn

• Gene Symbol: CHAC1
• Assay Reference Genome Location: Chr.15:40943932 on build GRCh38
• Cytoband: 15q15.1

Target Gene Details

• Entrez Gene ID: 79094
• Gene Name: ChaC glutathione specific gamma-glutamylcyclotransferase 1
• Gene Aliases: -
• Location: Chr.15:40942135-40956519 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHAC1	XM_017022563.1	1	1798	XP_016878052.1
	XM_017022564.1			XP_016878053.1
	XM_017022565.1	1	1798	XP_016878054.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1504	Chr.15:40936351 - 40969374 on Build GRCh38	Insertion	CHAC1 DLL4
esv2506979	Chr.15:40943121 - 40944102 on Build GRCh38	Insertion	CHAC1

More Information

Additional Information:

For this assay, SNP(s) [rs73402522] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

glutathione biosynthetic process
response to unfolded protein
Notch signaling pathway
negative regulation of protein processing
neurogenesis
negative regulation of Notch signaling pathway
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Function(s)

gamma-glutamylcyclotransferase activity
Notch binding
protein binding