Hs05268130_cn

• Gene Symbol: MARK2
• Assay Reference Genome Location: Chr.11:63867656 on build GRCh38
• Cytoband: 11q13.1

Target Gene Details

• Entrez Gene ID: 2011
• Gene Name: microtubule affinity regulating kinase 2
• Gene Aliases: EMK-1, EMK1, PAR-1, Par-1b, Par1b
• Location: Chr.11:63838928-63911020 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MARK2	NM_001039469.2			NP_001034558.2
	NM_001163296.1			NP_001156768.1
	NM_001163297.1			NP_001156769.1
	NM_004954.4			NP_004945.4
	XM_017017310.1			XP_016872799.1
	AB188493.1			BAD37141.1
	AK225766.1
	AK307858.1
	AY562187.1			AAT67601.1
	BC008771.2			AAH08771.2
	BC084540.1			AAH84540.1
	BM724555.1
	BX383836.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv555180	Chr.11:63748280 - 63945767 on Build GRCh38	Loss	NAA40 MARK2 C11orf95 RTN3 C11orf84 RCOR2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

microtubule cytoskeleton organization
mitophagy
neuron migration
protein phosphorylation
positive regulation of neuron projection development
Wnt signaling pathway
peptidyl-threonine phosphorylation
establishment of cell polarity
activation of protein kinase activity
intracellular signal transduction
establishment or maintenance of epithelial cell apical/basal polarity
protein autophosphorylation
regulation of axonogenesis
regulation of cytoskeleton organization
mitochondrion localization
cell-cell adhesion

Function(s)

magnesium ion binding
protein serine/threonine kinase activity
protein binding
ATP binding
lipid binding
protein kinase activator activity
poly(A) RNA binding
tau-protein kinase activity
cadherin binding involved in cell-cell adhesion