Hs04906465_cn

• Gene Symbol: MEA1
• Assay Reference Genome Location: Chr.6:42999396 on build GRCh38
• Cytoband: 6p21.1

Target Gene Details

• Entrez Gene ID: 4201
• Gene Name: male-enhanced antigen 1
• Gene Aliases: HYS, MEA
• Location: Chr.6:42980344-43016886 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MEA1	XM_017010868.1			XP_016866357.1
	AK309759.1

Target Gene Details

• Entrez Gene ID: 5528
• Gene Name: protein phosphatase 2 regulatory subunit B'delta
• Gene Aliases: B56D, MRD35
• Location: Chr.6:42984499-43012345 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP2R5D	NM_001270476.1			NP_001257405.1
	NM_006245.3			NP_006236.1
	NM_180976.2			NP_851307.1
	NM_180977.2			NP_851308.1
	AB000634.1			BAA20381.1
	AB000635.1			BAA20382.1
	AB451342.1
	AB451357.1
	AK122701.1
	AK290604.1
	AK291797.1
	AK299696.1
	BC001095.2			AAH01095.1
	BC001175.1			AAH01175.1
	BC010692.1			AAH10692.1
	D78360.1			BAA11372.1
	DA388594.1
	L76702.1			AAB69751.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830651	Chr.6:42845563 - 43000871 on Build GRCh38	Loss	GNMT MEA1 CNPY3 CNPY3-GNMT GLTSCR1L PTCRA C6orf226 RPL7L1 PEX6 PPP2R5D
esv3576145	Chr.6:42728097 - 43012090 on Build GRCh38	Gain	GNMT MEA1 CNPY3-GNMT C6orf226 RPL7L1 CNPY3 GLTSCR1L TBCC PTCRA LOC401261 ATP6V0CP3 PEX6 PPP2R5D
nsv602992	Chr.6:42948182 - 43110718 on Build GRCh38	Loss	GNMT MEA1 RRP36 CNPY3-GNMT KLHDC3 KLC4 CUL7 PEX6 MRPL2 PTK7 PPP2R5D
nsv1017398	Chr.6:42659705 - 43400998 on Build GRCh38	Gain	SLC22A7 PRPH2 CNPY3-GNMT KLC4 RPL7L1 MRPL2 UBR2 KLHDC3 GLTSCR1L PTCRA TTBK1 GNMT ZNF318 MEA1 RRP36 CUL7 C6orf226 SRF CNPY3 CRIP3 CUL9 TBCC DNPH1 LOC401261 ATP6V0CP3 PEX6 PTK7 PPP2R5D
nsv462929	Chr.6:42991162 - 43003012 on Build GRCh38	Loss	MEA1 PPP2R5D

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

spermatogenesis
male gonad development
cell differentiation
protein dephosphorylation
signal transduction
nervous system development
regulation of protein phosphatase type 2A activity

Function(s)

protein binding
protein serine/threonine phosphatase activity
protein phosphatase type 2A regulator activity