Hs04719591_cn

• Gene Symbol: CPOX
• Assay Reference Genome Location: Chr.3:98582871 on build GRCh38
• Cytoband: 3q11.2

Target Gene Details

• Entrez Gene ID: 1371
• Gene Name: coproporphyrinogen oxidase
• Gene Aliases: CPO, CPX, HCP
• Location: Chr.3:98568448-98593684 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CPOX	NM_000097.5			NP_000088.3
	XM_005247125.4			XP_005247182.1
	AK223481.1			BAD97201.1
	AK290140.1
	BC017210.2			AAH17210.1
	BC023551.2			AAH23551.1
	BC023554.2			AAH23554.1
	D16611.1			BAA04033.1
	Z28409.1			CAA82250.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834775	Chr.3:98451215 - 98648708 on Build GRCh38	Gain	OR5K1 GPR15 CPOX OR5K2 CLDND1
nsv591065	Chr.3:98485354 - 99047482 on Build GRCh38	Gain	ST3GAL6 ST3GAL6-AS1 GPR15 DCBLD2 CPOX OR5K2 CLDND1
dgv293n21	Chr.3:98382257 - 98598992 on Build GRCh38	Loss	OR5K3 OR5K1 GPR15 CPOX OR5K2 CLDND1
dgv4819n100	Chr.3:98565439 - 98662629 on Build GRCh38	Gain	CPOX

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidase, oxidoreductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

protoporphyrinogen IX biosynthetic process
heme biosynthetic process
response to iron ion
response to lead ion
response to insecticide
response to arsenic-containing substance
response to methylmercury
oxidation-reduction process

Function(s)

coproporphyrinogen oxidase activity
structural constituent of eye lens
protein homodimerization activity