Hs04673927_cn

• Gene Symbol: GDF7
• Assay Reference Genome Location: Chr.2:20668152 on build GRCh38
• Cytoband: 2p24.1

Target Gene Details

• Entrez Gene ID: 151449
• Gene Name: growth differentiation factor 7
• Gene Aliases: BMP12
• Location: Chr.2:20666664-20671490 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GDF7	NM_182828.3			NP_878248.2
	AB158468.1			BAD07014.1
	AF522369.1			AAP97720.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508828	Chr.2:20604120 - 20679078 on Build GRCh38	Insertion	GDF7 HS1BP3
nsv527901	Chr.2:20618698 - 20676626 on Build GRCh38	Loss	GDF7 HS1BP3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

axon guidance
positive regulation of pathway-restricted SMAD protein phosphorylation
roof plate formation
spinal cord association neuron differentiation
gland morphogenesis
BMP signaling pathway
epithelial cell differentiation
midbrain development
activin receptor signaling pathway
growth
regulation of apoptotic process
regulation of MAPK cascade
cell fate commitment
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
cell development
reproductive structure development
branching morphogenesis of an epithelial tube
forebrain morphogenesis
pathway-restricted SMAD protein phosphorylation
SMAD protein signal transduction
morphogenesis of an epithelial fold
positive regulation of tendon cell differentiation

Function(s)

cytokine activity
transforming growth factor beta receptor binding
protein binding
growth factor activity
protein homodimerization activity