Hs04257398_cn

• Gene Symbol: SEMA3F
• Assay Reference Genome Location: Chr.3:50167195 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 6405
• Gene Name: semaphorin 3F
• Gene Aliases: SEMA-IV, SEMA4, SEMAK
• Location: Chr.3:50155045-50189075 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA3F	NM_001318798.1			NP_001305727.1
	NM_001318800.1			NP_001305729.1
	NM_004186.4			NP_004177.3
	XM_005265381.4			XP_005265438.1
	XM_005265382.4			XP_005265439.1
	XM_006713290.3			XP_006713353.1
	XM_011533998.2			XP_011532300.1
	XM_011534000.2			XP_011532302.1
	AB209259.1			BAD92496.1
	BC042914.1			AAH42914.1
	BF058597.1
	BQ949723.1
	U33920.1			AAC50568.1
	U38276.1			AAB18276.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759148	Chr.3:50161045 - 50333946 on Build GRCh38	Loss	MIR5787 IFRD2 SEMA3B-AS1 LSMEM2 GNAI2 MIR566 SEMA3B RASSF1 HYAL2 TUSC2 HYAL3 NAT6 HYAL1 MIR6872 SLC38A3 GNAT1 SEMA3F
nsv523560	Chr.3:50134964 - 50314769 on Build GRCh38	Loss	MIR5787 IFRD2 SEMA3F-AS1 SEMA3B-AS1 LSMEM2 GNAI2 LOC107986035 MIR566 SEMA3B HYAL3 NAT6 HYAL1 MIR6872 SLC38A3 GNAT1 SEMA3F
dgv602n27	Chr.3:50140578 - 50287241 on Build GRCh38	Loss	MIR5787 SEMA3F-AS1 SEMA3B-AS1 LSMEM2 GNAI2 LOC107986035 MIR6872 MIR566 SEMA3B SLC38A3 GNAT1 SEMA3F
nsv834692	Chr.3:50161052 - 50356033 on Build GRCh38	Loss	MIR5787 IFRD2 SEMA3B-AS1 LSMEM2 TMEM115 GNAI2 MIR566 SEMA3B NPRL2 RASSF1 RASSF1-AS1 HYAL2 TUSC2 HYAL3 NAT6 HYAL1 ZMYND10 MIR6872 SLC38A3 GNAT1 CYB561D2 SEMA3F
dgv8316n54	Chr.3:50115923 - 50299991 on Build GRCh38	Loss	MIR5787 IFRD2 SEMA3F-AS1 SEMA3B-AS1 LSMEM2 GNAI2 LOC107986035 MIR566 SEMA3B HYAL3 NAT6 HYAL1 MIR6872 SLC38A3 GNAT1 RBM5 SEMA3F
nsv515986	Chr.3:50066874 - 50254353 on Build GRCh38	Loss	MIR5787 SEMA3F-AS1 GNAI2 LOC107986035 MIR566 RBM5-AS1 SLC38A3 GNAT1 RBM5 SEMA3F RBM6
nsv470561	Chr.3:50121341 - 50547568 on Build GRCh38	Loss	SEMA3F-AS1 LSMEM2 TMEM115 GNAI2 MIR566 NPRL2 RASSF1 CACNA2D2 HYAL2 TUSC2 NAT6 GNAT1 CYB561D2 SEMA3F MIR5787 IFRD2 SEMA3B-AS1 LOC107986035 SEMA3B RASSF1-AS1 HYAL3 HYAL1 ZMYND10 MIR6872 SLC38A3
nsv523662	Chr.3:50107518 - 50547568 on Build GRCh38	Loss	SEMA3F-AS1 LSMEM2 TMEM115 GNAI2 MIR566 NPRL2 RASSF1 CACNA2D2 HYAL2 TUSC2 NAT6 GNAT1 CYB561D2 SEMA3F MIR5787 IFRD2 SEMA3B-AS1 LOC107986035 SEMA3B RASSF1-AS1 HYAL3 HYAL1 ZMYND10 MIR6872 SLC38A3 RBM5
nsv834690	Chr.3:50064402 - 50263192 on Build GRCh38	Loss	MIR5787 SEMA3F-AS1 GNAI2 LOC107986035 MIR566 RBM5-AS1 SLC38A3 GNAT1 RBM5 SEMA3F RBM6
nsv954855	Chr.3:50152468 - 50439169 on Build GRCh38	Deletion	SEMA3F-AS1 LSMEM2 TMEM115 GNAI2 MIR566 NPRL2 RASSF1 CACNA2D2 HYAL2 TUSC2 NAT6 GNAT1 CYB561D2 SEMA3F MIR5787 IFRD2 SEMA3B-AS1 LOC107986035 SEMA3B RASSF1-AS1 HYAL3 HYAL1 ZMYND10 MIR6872 SLC38A3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
axon guidance
facial nerve structural organization
trigeminal nerve structural organization
nerve development
branchiomotor neuron axon guidance
positive regulation of cell migration
ventral trunk neural crest cell migration
negative regulation of axon extension involved in axon guidance
axon extension involved in axon guidance
negative chemotaxis
sympathetic ganglion development
semaphorin-plexin signaling pathway
sympathetic neuron projection extension
sympathetic neuron projection guidance
neural crest cell migration involved in autonomic nervous system development
semaphorin-plexin signaling pathway involved in neuron projection guidance
semaphorin-plexin signaling pathway involved in axon guidance

Function(s)

semaphorin receptor binding
neuropilin binding
chemorepellent activity