Hs04249504_cn

• Gene Symbol: CD86
• Assay Reference Genome Location: Chr.3:122067584 on build GRCh38
• Cytoband: 3q13.33

Target Gene Details

• Entrez Gene ID: 942
• Gene Name: CD86 molecule
• Gene Aliases: B7-2, B7.2, B70, CD28LG2, LAB72
• Location: Chr.3:122055362-122121143 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CD86	NM_001206924.1			NP_001193853.1
	NM_001206925.1			NP_001193854.1
	NM_175862.4			NP_787058.4
	AK291497.1
	AK294663.1
	AK301237.1
	AK313103.1
	AK316203.1
	BC040261.1			AAH40261.1
	DA619360.1
	L25259.1			AAA58389.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv33139	Chr.3:121781553 - 122372984 on Build GRCh38	Loss	ILDR1 EAF2 IQCB1 CSTA CASR CCDC58 SLC15A2 CD86

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

response to yeast
adaptive immune response
T cell proliferation involved in immune response
negative regulation of T cell anergy
immune response
cell-cell signaling
aging
positive regulation of cell proliferation
regulation of phosphatidylinositol 3-kinase signaling
T cell costimulation
toll-like receptor 3 signaling pathway
response to interferon-gamma
positive regulation of activated T cell proliferation
T cell activation
B cell activation
response to drug
myeloid dendritic cell differentiation
positive regulation of lymphotoxin A biosynthetic process
positive regulation of interleukin-2 biosynthetic process
positive regulation of interleukin-4 biosynthetic process
positive regulation of T-helper 2 cell differentiation
positive regulation of transcription, DNA-templated
viral entry into host cell
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
defense response to virus
cellular response to lipopolysaccharide
cellular response to metal ion
cellular response to cytokine stimulus

Function(s)

virus receptor activity
receptor activity
receptor binding
protein binding
coreceptor activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity