Hs03965577_cn

• Gene Symbol: SUZ12
• Assay Reference Genome Location: Chr.17:31986921 on build GRCh38
• Cytoband: 17q11.2

Target Gene Details

• Entrez Gene ID: 23512
• Gene Name: SUZ12 polycomb repressive complex 2 subunit
• Gene Aliases: CHET9, JJAZ1
• Location: Chr.17:31937010-32001045 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SUZ12	NM_001321207.1			NP_001308136.1
	NM_015355.3			NP_056170.2
	XM_006721794.3			XP_006721857.1
	XM_017024409.1			XP_016879898.1
	AK074333.1
	AK290014.1
	BC015704.1			AAH15704.1
	D63881.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1062194	Chr.17:31755256 - 32041289 on Build GRCh38	Gain	UTP6 LRRC37B SUZ12 LOC105371727 COPRS SH3GL1P1
esv2758684	Chr.17:31894702 - 32210963 on Build GRCh38	Gain	UTP6 LRRC37B RHOT1 ARGFXP2 SUZ12 LOC105371730 LOC105371727 LOC107985082 SH3GL1P1
nsv1067240	Chr.17:31892481 - 32005581 on Build GRCh38	Gain	UTP6 SUZ12 LOC105371727

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
positive regulation of cell proliferation
histone methylation
histone ubiquitination
negative regulation of cell differentiation
negative regulation of gene expression, epigenetic

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
RNA binding
protein binding
chromatin DNA binding
methylated histone binding
histone methyltransferase activity
metal ion binding