Hs03957448_cn

• Gene Symbol: COX10
• Assay Reference Genome Location: Chr.17:14079439 on build GRCh38
• Cytoband: 17p12

Target Gene Details

• Entrez Gene ID: 1352
• Gene Name: COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor
• Gene Aliases: -
• Location: Chr.17:14069402-14208679 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
COX10	NM_001303.3			NP_001294.2
	AK294213.1
	AK295925.1
	AK312718.1
	BC000060.2			AAH00060.1
	BC006394.2			AAH06394.1
	BT006985.1			AAP35631.1
	DA200545.1
	U09466.1			AAA21148.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2758675	Chr.17:13977924 - 14225239 on Build GRCh38	Loss	COX10 COX10-AS1 CDRT15P1
esv3640012	Chr.17:14037121 - 14081238 on Build GRCh38	Loss	COX10 COX10-AS1
nsv1056267	Chr.17:13835722 - 14236763 on Build GRCh38	Gain	COX10 LOC100506974 COX10-AS1 CDRT15 CDRT15P1
nsv574377	Chr.17:13548048 - 14439233 on Build GRCh38	Gain	HS3ST3B1 COX10 LOC100506974 HS3ST3A1 COX10-AS1 CDRT15 CDRT15P1 MGC12916
nsv1055511	Chr.17:14042329 - 14191370 on Build GRCh38	Loss	COX10 COX10-AS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

acyltransferase

Gene Ontology Categories:

Process(es)

mitochondrial fission
mitochondrial electron transport, cytochrome c to oxygen
heme biosynthetic process
heme a biosynthetic process
respiratory chain complex IV assembly
aerobic respiration
cellular respiration
heme O biosynthetic process
hydrogen ion transmembrane transport

Function(s)

cytochrome-c oxidase activity
farnesyltranstransferase activity
protoheme IX farnesyltransferase activity