Hs03941987_cn

• Gene Symbol: DHODH
• Assay Reference Genome Location: Chr.16:72015471 on build GRCh38
• Cytoband: 16q22.2

Target Gene Details

• Entrez Gene ID: 1723
• Gene Name: dihydroorotate dehydrogenase (quinone)
• Gene Aliases: DHOdehase, POADS, URA1
• Location: Chr.16:72008744-72027659 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DHODH	NM_001361.4			NP_001352.2
	XM_005255827.3			XP_005255884.1
	XM_005255829.3			XP_005255886.1
	XM_017022990.1			XP_016878479.1
	AK292293.1
	AU130529.1
	BC065245.1			AAH65245.1
	BI253747.1
	BM795077.1
	M94065.1			AAA50163.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1055854	Chr.16:71888241 - 72048987 on Build GRCh38	Loss	TXNL4B IST1 DHODH PKD1L3
esv3582296	Chr.16:71965845 - 72027933 on Build GRCh38	Loss	DHODH PKD1L3
esv2758654	Chr.16:71942441 - 72240448 on Build GRCh38	Gain	PMFBP1 TXNL4B HP DHX38 DHODH PKD1L3 HPR
esv2714683	Chr.16:71950823 - 72151945 on Build GRCh38	Deletion	PMFBP1 TXNL4B HP DHX38 DHODH PKD1L3 HPR
nsv833273	Chr.16:71937902 - 72118955 on Build GRCh38	Loss	PMFBP1 TXNL4B HP DHX38 DHODH PKD1L3 HPR

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

dehydrogenase

Gene Ontology Categories:

Process(es)

'de novo' pyrimidine nucleobase biosynthetic process
female pregnancy
lactation
response to caffeine
response to drug
response to starvation
positive regulation of apoptotic process
'de novo' UMP biosynthetic process
pyrimidine nucleoside biosynthetic process
oxidation-reduction process
regulation of mitochondrial fission

Function(s)

dihydroorotate dehydrogenase activity
drug binding
FMN binding
ubiquinone binding