Hs03787351_cn

• Gene Symbol: DLG2
• Assay Reference Genome Location: Chr.11:83463084 on build GRCh38
• Cytoband: 11q14.1

Target Gene Details

• Entrez Gene ID: 1740
• Gene Name: discs large MAGUK scaffold protein 2
• Gene Aliases: PPP1R58, PSD-93, PSD93, chapsyn-110
• Location: Chr.11:83455009-85628534 on Build GRCh38
• Assay Gene Location: Within Intron 41

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DLG2	NM_001142699.1			NP_001136171.1
	NM_001142700.1			NP_001136172.1
	NM_001142702.1			NP_001136174.1
	NM_001206769.1			NP_001193698.1
	NM_001300983.1			NP_001287912.1
	NM_001364.3			NP_001355.2
	XM_005273810.4			XP_005273867.1
	XM_005273811.4			XP_005273868.1
	XM_011544778.2			XP_011543080.1
	XM_011544780.2			XP_011543082.1
	XM_011544782.2			XP_011543084.1
	XM_011544788.2			XP_011543090.1
	XM_017017254.1			XP_016872743.1
	XM_017017255.1			XP_016872744.1
	XM_017017256.1			XP_016872745.1
	XM_017017257.1			XP_016872746.1
	XM_017017258.1			XP_016872747.1
	XM_017017259.1			XP_016872748.1
	XM_017017260.1			XP_016872749.1
	XM_017017261.1			XP_016872750.1
	XM_017017262.1			XP_016872751.1
	XM_017017263.1			XP_016872752.1
	XM_017017264.1			XP_016872753.1
	XM_017017265.1			XP_016872754.1
	XM_017017266.1			XP_016872755.1
	XM_017017267.1			XP_016872756.1
	XM_017017268.1			XP_016872757.1
	XM_017017269.1			XP_016872758.1
	XM_017017270.1			XP_016872759.1
	XM_017017271.1			XP_016872760.1
	XM_017017272.1			XP_016872761.1
	XM_017017273.1			XP_016872762.1
	XM_017017274.1			XP_016872763.1
	XM_017017275.1			XP_016872764.1
	XM_017017276.1			XP_016872765.1
	XM_017017277.1			XP_016872766.1
	XM_017017278.1			XP_016872767.1
	XM_017017279.1			XP_016872768.1
	XM_017017280.1			XP_016872769.1
	XM_017017281.1			XP_016872770.1
	XM_017017282.1			XP_016872771.1
	XM_017017283.1			XP_016872772.1
	XM_017017284.1			XP_016872773.1
	XM_017017285.1			XP_016872774.1
	XM_017017286.1			XP_016872775.1
	XM_017017287.1			XP_016872776.1
	XM_017017288.1			XP_016872777.1
	XM_017017289.1			XP_016872778.1
	XM_017017290.1			XP_016872779.1
	XM_017017291.1			XP_016872780.1
	XM_017017292.1			XP_016872781.1
	AK126776.1			BAC86685.1
	AK294375.1
	AK295094.1
	AK295624.1
	AK299778.1
	AK299797.1
	CR749820.1			CAH18680.1
	CR933674.1			CAI45970.1
	KJ535093.1
	U32376.1			AAB04949.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv33531	Chr.11:82520885 - 83805659 on Build GRCh38	Loss	FAM181B LOC100506282 PCF11 CCDC90B ANKRD42 RAB30-AS1 LOC102724712 SNORA70E DLG2 DDIAS PCF11-AS1 PRCP RAB30

More Information

Additional Information:

For this assay, SNP(s) [rs78682100] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

chemical synaptic transmission
nervous system development
negative regulation of phosphatase activity
sensory perception of pain
receptor clustering
establishment or maintenance of epithelial cell apical/basal polarity
GMP metabolic process
GDP metabolic process
receptor localization to synapse

Function(s)

guanylate kinase activity
protein binding
kinase binding
ionotropic glutamate receptor binding