Hs03751024_cn

• Gene Symbol: PRKG1
• Assay Reference Genome Location: Chr.10:50995567 on build GRCh38
• Cytoband: 10q11.23

Target Gene Details

• Entrez Gene ID: 5592
• Gene Name: protein kinase, cGMP-dependent, type I
• Gene Aliases: AAT8, PKG, PRKG1B, PRKGR1B, cGK, cGK 1, cGK1, cGKI, cGKI-BETA, cGKI-alpha
• Location: Chr.10:50991151-52298350 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRKG1	NM_001098512.2			NP_001091982.1
	AK300110.1
	D45864.1			BAA08297.1
	DC310312.1
	DC379897.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv129e214	Chr.10:50994861 - 50998312 on Build GRCh38	Loss	PRKG1
nsv831873	Chr.10:50950850 - 51139780 on Build GRCh38	Gain	PRKG1 LOC102724719
nsv831872	Chr.10:50903568 - 51058777 on Build GRCh38	Gain	PRKG1
esv3623224	Chr.10:50995215 - 50998263 on Build GRCh38	Gain	PRKG1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

neuron migration
protein phosphorylation
signal transduction
dendrite development
cGMP-mediated signaling
actin cytoskeleton organization
forebrain development
regulation of GTPase activity
relaxation of vascular smooth muscle
negative regulation of platelet aggregation
mitophagy in response to mitochondrial depolarization

Function(s)

protein serine/threonine kinase activity
cGMP-dependent protein kinase activity
calcium channel regulator activity
protein binding
ATP binding
cGMP binding