Hs03722622_cn

• Gene Symbol: NOXA1
• Assay Reference Genome Location: Chr.9:137424035 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10811
• Gene Name: NADPH oxidase activator 1
• Gene Aliases: NY-CO-31, SDCCAG31, p51NOX
• Location: Chr.9:137423372-137434406 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NOXA1	NM_001256067.1			NP_001242996.1
	NM_001256068.1			NP_001242997.1
	NM_006647.1			NP_006638.1
	XM_011518158.2			XP_011516460.1
	XM_011518159.1			XP_011516461.1
	XM_011518160.1			XP_011516462.1
	AB095031.1			BAC76710.1
	AK098341.1
	AY255769.1			AAP13480.1
	AY927790.1			AAY16126.1
	AY927791.1			AAY16127.1
	BC041594.1			AAH41594.1
	BC110840.1			AAI10841.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1049808	Chr.9:137356366 - 137438026 on Build GRCh38	Gain	ENTPD8 EXD3 NOXA1
nsv951208	Chr.9:137379349 - 137467948 on Build GRCh38	Deletion	ENTPD8 NSMF MIR7114 PNPLA7 EXD3 NOXA1
nsv6771	Chr.9:137412670 - 137444666 on Build GRCh38	Insertion	ENTPD8 EXD3 NOXA1
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	ENTPD8 EXD3 NOXA1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	ABCA2 C9orf142 RABL6 NSMF UAP1L1 CCDC183 PHPT1 DPP7 FUT7 EDF1 ANAPC2 C9orf173-AS1 MAN1B1 C8G FAM166A SAPCD2 NRARP C9orf139 ENTPD2 LCNL1 MIR4292 CLIC3 MIR3621 LRRC26 MIR7114 MIR4479 MAN1B1-AS1 MAMDC4 PTGDS EXD3 SSNA1 NELFB LOC101930307 TMEM203 ENTPD8 TPRN TUBB4B PNPLA7 LCN12 RNF208 TRAF2 TMEM210 STPG3 CCDC183-AS1 CYSRT1 RNF224 TOR4A FBXW5 GRIN1 NDOR1 NOXA1 PRR31 C9orf172 SLC34A3 NPDC1
esv3573431	Chr.9:137415581 - 137425256 on Build GRCh38	Loss	EXD3 NOXA1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	CYSRT1 RNF224 TOR4A FAM166A GRIN1 NDOR1 EXD3 NRARP SSNA1 ANAPC2 NELFB NOXA1 C9orf173-AS1 SLC34A3 TMEM203 ENTPD8 TPRN TUBB4B RNF208 TMEM210 MIR3621 LRRC26 STPG3

More Information

Additional Information:

For this assay, SNP(s) [rs116280312] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator

Gene Ontology Categories:

Process(es)

superoxide metabolic process
regulation of hydrogen peroxide metabolic process
positive regulation of catalytic activity
regulation of respiratory burst

Function(s)

protein binding
superoxide-generating NADPH oxidase activator activity
SH3 domain binding
enzyme binding
Rac GTPase binding