Hs03698480_cn

• Gene Symbol: BOP1
• Assay Reference Genome Location: Chr.8:144282070 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 23246
• Gene Name: block of proliferation 1
• Gene Aliases: -
• Location: Chr.8:144262046-144291438 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BOP1	NM_015201.4			NP_056016.1
	AB060694.1			BAB70666.1
	AK024840.1
	AK290677.1
	AK293719.1
	AK315612.1
	BC001086.2			AAH01086.2
	BC005160.2			AAH05160.2
	BC007274.1			AAH07274.1
	BC013787.1			AAH13787.1
	BC013980.2			AAH13980.1
	BC017674.2			AAH17674.1
	BQ711345.1
	D50914.1			BAA09473.1
	DA510177.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	CYHR1 ADCK5 FOXH1 FBXL6 HSF1 RECQL4 LOC101928902 MIR1234 PPP1R16A SCRT1 VPS28 MIR939 GPT CPSF1 LOC101928953 DGAT1 TMEM249 SLC39A4 MIR6849 TONSL-AS1 BOP1 MIR6893 MFSD3 MIR6848 TONSL SLC52A2 KIFC2
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	CYHR1 EXOSC4 PARP10 ADCK5 MIR7112 FOXH1 MIR661 FBXL6 HGH1 LRRC14 PLEC HSF1 CYC1 RECQL4 LOC101928902 MIR1234 SHARPIN MIR6847 WDR97 PPP1R16A SCRT1 VPS28 GPAA1 MIR939 GPT CPSF1 LOC101928953 DGAT1 OPLAH TMEM249 SLC39A4 MIR6849 TONSL-AS1 BOP1 MAF1 MIR6893 MROH1 SPATC1 MFSD3 MIR6848 MIR6846 SCX TONSL SMPD5 SLC52A2 GRINA KIFC2
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	CYHR1 EXOSC4 PARP10 ADCK5 MIR7112 FOXH1 MIR661 FBXL6 HGH1 LRRC14 PLEC HSF1 CYC1 RECQL4 LOC101928902 MIR1234 SHARPIN MIR6847 WDR97 PPP1R16A SCRT1 VPS28 GPAA1 MIR939 GPT CPSF1 LOC101928953 DGAT1 OPLAH TMEM249 SLC39A4 MIR6849 TONSL-AS1 BOP1 MAF1 MIR6893 MROH1 SPATC1 MFSD3 MIR6848 MIR6846 SCX TONSL SMPD5 SLC52A2 GRINA KIFC2
nsv1025071	Chr.8:144044224 - 144300847 on Build GRCh38	Gain	EXOSC4 MIR7112 OPLAH HGH1 BOP1 HSF1 CYC1 MAF1 MROH1 SPATC1 SHARPIN MIR6846 MIR6847 SCX WDR97 SMPD5 GPAA1
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	LRRC24 CYHR1 EXOSC4 ADCK5 MIR7112 FOXH1 ZNF251 FBXL6 HGH1 LRRC14 HSF1 CYC1 RECQL4 LOC101928902 MIR1234 SHARPIN MIR6847 WDR97 PPP1R16A SCRT1 VPS28 GPAA1 MIR939 GPT CPSF1 LOC101928953 C8orf82 DGAT1 OPLAH TMEM249 SLC39A4 MIR6849 TONSL-AS1 BOP1 MAF1 MIR6893 MROH1 SPATC1 MFSD3 ARHGAP39 MIR6848 MIR6846 SCX TONSL SMPD5 SLC52A2 KIFC2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein

Gene Ontology Categories:

Process(es)

cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
cell proliferation
ribosome biogenesis
regulation of cell cycle

Function(s)

protein binding
ribonucleoprotein complex binding
poly(A) RNA binding