Hs03668950_cn

• Gene Symbol: BOP1
• Assay Reference Genome Location: Chr.8:144280126 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 23246
• Gene Name: block of proliferation 1
• Gene Aliases: -
• Location: Chr.8:144262046-144291438 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BOP1	NM_015201.4			NP_056016.1
	AB060694.1			BAB70666.1
	AK024840.1
	AK290677.1
	AK293719.1
	AK315612.1
	BC001086.2			AAH01086.2
	BC005160.2			AAH05160.2
	BC007274.1			AAH07274.1
	BC013787.1			AAH13787.1
	BC013980.2			AAH13980.1
	BC017674.2			AAH17674.1
	BQ711345.1
	D50914.1			BAA09473.1
	DA510177.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	HSF1 MIR6849 KIFC2 SCRT1 CPSF1 TONSL MIR6893 ADCK5 MFSD3 LOC101928953 MIR1234 DGAT1 SLC39A4 MIR939 GPT RECQL4 LOC101928902 PPP1R16A FOXH1 CYHR1 FBXL6 SLC52A2 BOP1 TMEM249 MIR6848 VPS28 TONSL-AS1
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	HSF1 PLEC SMPD5 MIR6849 KIFC2 MAF1 CYC1 SCRT1 PARP10 CPSF1 TONSL MIR6893 MROH1 OPLAH SCX MIR661 ADCK5 SPATC1 MIR7112 MFSD3 LRRC14 GPAA1 WDR97 LOC101928953 MIR1234 DGAT1 SLC39A4 MIR939 GPT RECQL4 LOC101928902 PPP1R16A SHARPIN FOXH1 HGH1 GRINA MIR6847 CYHR1 FBXL6 MIR6846 SLC52A2 EXOSC4 BOP1 TMEM249 MIR6848 VPS28 TONSL-AS1
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	HSF1 PLEC SMPD5 MIR6849 KIFC2 MAF1 CYC1 SCRT1 PARP10 CPSF1 TONSL MIR6893 MROH1 OPLAH SCX MIR661 ADCK5 SPATC1 MIR7112 MFSD3 LRRC14 GPAA1 WDR97 LOC101928953 MIR1234 DGAT1 SLC39A4 MIR939 GPT RECQL4 LOC101928902 PPP1R16A SHARPIN FOXH1 HGH1 GRINA MIR6847 CYHR1 FBXL6 MIR6846 SLC52A2 EXOSC4 BOP1 TMEM249 MIR6848 VPS28 TONSL-AS1
nsv1025071	Chr.8:144044224 - 144300847 on Build GRCh38	Gain	HSF1 SMPD5 MAF1 CYC1 SHARPIN MROH1 HGH1 OPLAH MIR6847 SCX MIR6846 SPATC1 EXOSC4 BOP1 MIR7112 GPAA1 WDR97
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	HSF1 SMPD5 MIR6849 KIFC2 MAF1 LRRC24 CYC1 SCRT1 CPSF1 TONSL MIR6893 MROH1 OPLAH SCX ADCK5 C8orf82 SPATC1 MIR7112 MFSD3 LRRC14 GPAA1 WDR97 LOC101928953 ZNF251 MIR1234 DGAT1 SLC39A4 MIR939 GPT RECQL4 LOC101928902 PPP1R16A SHARPIN FOXH1 HGH1 MIR6847 CYHR1 FBXL6 MIR6846 SLC52A2 EXOSC4 BOP1 TMEM249 MIR6848 VPS28 TONSL-AS1 ARHGAP39

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein

Gene Ontology Categories:

Process(es)

cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
cell proliferation
ribosome biogenesis
regulation of cell cycle

Function(s)

protein binding
ribonucleoprotein complex binding
poly(A) RNA binding