Hs03667203_cn

• Gene Symbol: BOP1
• Assay Reference Genome Location: Chr.8:144286926 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 23246
• Gene Name: block of proliferation 1
• Gene Aliases: -
• Location: Chr.8:144262046-144291438 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BOP1	NM_015201.4			NP_056016.1
	AB060694.1			BAB70666.1
	AK024840.1
	AK290677.1
	AK293719.1
	AK315612.1
	BC001086.2			AAH01086.2
	BC005160.2			AAH05160.2
	BC007274.1			AAH07274.1
	BC013787.1			AAH13787.1
	BC013980.2			AAH13980.1
	BC017674.2			AAH17674.1
	BQ711345.1
	D50914.1			BAA09473.1
	DA510177.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	TMEM249 FBXL6 LOC101928953 LOC101928902 TONSL SLC52A2 DGAT1 MIR6849 SLC39A4 TONSL-AS1 HSF1 KIFC2 VPS28 RECQL4 FOXH1 MIR1234 PPP1R16A BOP1 MIR6848 MFSD3 CYHR1 CPSF1 MIR6893 ADCK5 MIR939 SCRT1 GPT
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	TMEM249 MROH1 FBXL6 LOC101928953 GPAA1 LOC101928902 WDR97 TONSL GRINA SLC52A2 DGAT1 MIR661 MIR6849 PARP10 SLC39A4 EXOSC4 TONSL-AS1 MAF1 MIR6846 HSF1 PLEC KIFC2 VPS28 RECQL4 MIR7112 FOXH1 MIR1234 PPP1R16A HGH1 BOP1 MIR6848 MFSD3 CYHR1 CPSF1 MIR6847 SMPD5 OPLAH SPATC1 CYC1 SCX MIR6893 LRRC14 ADCK5 MIR939 SCRT1 SHARPIN GPT
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	TMEM249 MROH1 FBXL6 LOC101928953 GPAA1 LOC101928902 WDR97 TONSL GRINA SLC52A2 DGAT1 MIR661 MIR6849 PARP10 SLC39A4 EXOSC4 TONSL-AS1 MAF1 MIR6846 HSF1 PLEC KIFC2 VPS28 RECQL4 MIR7112 FOXH1 MIR1234 PPP1R16A HGH1 BOP1 MIR6848 MFSD3 CYHR1 CPSF1 MIR6847 SMPD5 OPLAH SPATC1 CYC1 SCX MIR6893 LRRC14 ADCK5 MIR939 SCRT1 SHARPIN GPT
nsv1025071	Chr.8:144044224 - 144300847 on Build GRCh38	Gain	MIR7112 MROH1 HGH1 GPAA1 BOP1 WDR97 MIR6847 SMPD5 OPLAH SPATC1 CYC1 EXOSC4 SCX MAF1 MIR6846 HSF1 SHARPIN
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	TMEM249 ARHGAP39 MROH1 FBXL6 LOC101928953 GPAA1 LOC101928902 WDR97 TONSL SLC52A2 DGAT1 MIR6849 SLC39A4 EXOSC4 TONSL-AS1 MAF1 MIR6846 HSF1 KIFC2 VPS28 RECQL4 MIR7112 FOXH1 MIR1234 LRRC24 PPP1R16A HGH1 BOP1 MIR6848 MFSD3 ZNF251 CYHR1 CPSF1 MIR6847 SMPD5 OPLAH SPATC1 CYC1 SCX MIR6893 LRRC14 C8orf82 ADCK5 MIR939 SCRT1 SHARPIN GPT

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein

Gene Ontology Categories:

Process(es)

cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
cell proliferation
ribosome biogenesis
regulation of cell cycle

Function(s)

protein binding
ribonucleoprotein complex binding
poly(A) RNA binding