Hs03661643_cn

• Gene Symbol: BOP1
• Assay Reference Genome Location: Chr.8:144284507 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 23246
• Gene Name: block of proliferation 1
• Gene Aliases: -
• Location: Chr.8:144262046-144291438 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BOP1	NM_015201.4			NP_056016.1
	AB060694.1			BAB70666.1
	AK024840.1
	AK290677.1
	AK293719.1
	AK315612.1
	BC001086.2			AAH01086.2
	BC005160.2			AAH05160.2
	BC007274.1			AAH07274.1
	BC013787.1			AAH13787.1
	BC013980.2			AAH13980.1
	BC017674.2			AAH17674.1
	BQ711345.1
	D50914.1			BAA09473.1
	DA510177.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	MIR939 MFSD3 CYHR1 RECQL4 LOC101928953 GPT MIR6849 MIR6848 TONSL-AS1 MIR6893 TMEM249 KIFC2 CPSF1 HSF1 DGAT1 SLC52A2 SCRT1 VPS28 TONSL FBXL6 LOC101928902 MIR1234 PPP1R16A FOXH1 SLC39A4 BOP1 ADCK5
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	SPATC1 PARP10 MIR939 MFSD3 HGH1 CYHR1 RECQL4 LOC101928953 GPT CYC1 OPLAH MIR6849 PLEC MIR7112 MIR6848 LRRC14 GRINA TONSL-AS1 MIR6893 MIR6846 TMEM249 EXOSC4 SMPD5 GPAA1 WDR97 KIFC2 CPSF1 HSF1 MIR6847 DGAT1 SLC52A2 SCRT1 VPS28 TONSL MIR661 FBXL6 MAF1 LOC101928902 MIR1234 PPP1R16A MROH1 SCX SHARPIN FOXH1 SLC39A4 BOP1 ADCK5
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	SPATC1 PARP10 MIR939 MFSD3 HGH1 CYHR1 RECQL4 LOC101928953 GPT CYC1 OPLAH MIR6849 PLEC MIR7112 MIR6848 LRRC14 GRINA TONSL-AS1 MIR6893 MIR6846 TMEM249 EXOSC4 SMPD5 GPAA1 WDR97 KIFC2 CPSF1 HSF1 MIR6847 DGAT1 SLC52A2 SCRT1 VPS28 TONSL MIR661 FBXL6 MAF1 LOC101928902 MIR1234 PPP1R16A MROH1 SCX SHARPIN FOXH1 SLC39A4 BOP1 ADCK5
nsv1025071	Chr.8:144044224 - 144300847 on Build GRCh38	Gain	SPATC1 HSF1 MIR6847 HGH1 CYC1 MAF1 OPLAH MIR7112 MROH1 SCX MIR6846 EXOSC4 SMPD5 GPAA1 SHARPIN WDR97 BOP1
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	SPATC1 MIR939 MFSD3 HGH1 CYHR1 RECQL4 LRRC24 LOC101928953 GPT CYC1 OPLAH MIR6849 MIR7112 C8orf82 MIR6848 LRRC14 TONSL-AS1 MIR6893 MIR6846 TMEM249 EXOSC4 SMPD5 GPAA1 WDR97 KIFC2 CPSF1 HSF1 MIR6847 DGAT1 ZNF251 SLC52A2 SCRT1 VPS28 TONSL ARHGAP39 FBXL6 MAF1 LOC101928902 MIR1234 PPP1R16A MROH1 SCX SHARPIN FOXH1 SLC39A4 BOP1 ADCK5

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein

Gene Ontology Categories:

Process(es)

cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
cell proliferation
ribosome biogenesis
regulation of cell cycle

Function(s)

protein binding
ribonucleoprotein complex binding
poly(A) RNA binding