Hs03656107_cn

• Gene Symbol: BOP1
• Assay Reference Genome Location: Chr.8:144283329 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 23246
• Gene Name: block of proliferation 1
• Gene Aliases: -
• Location: Chr.8:144262046-144291438 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BOP1	NM_015201.4			NP_056016.1
	AB060694.1			BAB70666.1
	AK024840.1
	AK290677.1
	AK293719.1
	AK315612.1
	BC001086.2			AAH01086.2
	BC005160.2			AAH05160.2
	BC007274.1			AAH07274.1
	BC013787.1			AAH13787.1
	BC013980.2			AAH13980.1
	BC017674.2			AAH17674.1
	BQ711345.1
	D50914.1			BAA09473.1
	DA510177.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	CPSF1 KIFC2 FBXL6 MFSD3 SLC39A4 DGAT1 TONSL-AS1 TMEM249 LOC101928902 RECQL4 CYHR1 LOC101928953 FOXH1 BOP1 ADCK5 GPT MIR1234 MIR6848 PPP1R16A SCRT1 HSF1 MIR6849 TONSL MIR6893 MIR939 VPS28 SLC52A2
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	CPSF1 LRRC14 MAF1 KIFC2 FBXL6 PLEC MFSD3 SLC39A4 DGAT1 TONSL-AS1 HGH1 TMEM249 LOC101928902 RECQL4 SPATC1 CYHR1 LOC101928953 MIR661 FOXH1 WDR97 BOP1 MROH1 SMPD5 CYC1 ADCK5 SHARPIN MIR6847 SCX GPT MIR1234 EXOSC4 MIR6848 PPP1R16A PARP10 MIR6846 SCRT1 HSF1 OPLAH GRINA MIR6849 TONSL MIR6893 MIR939 VPS28 GPAA1 MIR7112 SLC52A2
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	CPSF1 LRRC14 MAF1 KIFC2 FBXL6 PLEC MFSD3 SLC39A4 DGAT1 TONSL-AS1 HGH1 TMEM249 LOC101928902 RECQL4 SPATC1 CYHR1 LOC101928953 MIR661 FOXH1 WDR97 BOP1 MROH1 SMPD5 CYC1 ADCK5 SHARPIN MIR6847 SCX GPT MIR1234 EXOSC4 MIR6848 PPP1R16A PARP10 MIR6846 SCRT1 HSF1 OPLAH GRINA MIR6849 TONSL MIR6893 MIR939 VPS28 GPAA1 MIR7112 SLC52A2
nsv1025071	Chr.8:144044224 - 144300847 on Build GRCh38	Gain	WDR97 MAF1 BOP1 MROH1 SMPD5 CYC1 SHARPIN MIR6847 SCX EXOSC4 HGH1 MIR6846 HSF1 SPATC1 OPLAH GPAA1 MIR7112
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	LRRC24 CPSF1 LRRC14 MAF1 KIFC2 FBXL6 MFSD3 SLC39A4 DGAT1 TONSL-AS1 HGH1 TMEM249 LOC101928902 RECQL4 SPATC1 CYHR1 LOC101928953 FOXH1 C8orf82 ARHGAP39 WDR97 BOP1 MROH1 SMPD5 CYC1 ADCK5 SHARPIN MIR6847 SCX GPT MIR1234 EXOSC4 MIR6848 PPP1R16A MIR6846 ZNF251 SCRT1 HSF1 OPLAH MIR6849 TONSL MIR6893 MIR939 VPS28 GPAA1 MIR7112 SLC52A2

More Information

Additional Information:

For this assay, SNP(s) [rs67384412] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein

Gene Ontology Categories:

Process(es)

cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
cell proliferation
ribosome biogenesis
regulation of cell cycle

Function(s)

protein binding
ribonucleoprotein complex binding
poly(A) RNA binding