Hs03399948_cn

• Gene Symbol: GCG
• Assay Reference Genome Location: Chr.2:162151297 on build GRCh38
• Cytoband: 2q24.2

Target Gene Details

• Entrez Gene ID: 2641
• Gene Name: glucagon
• Gene Aliases: GLP1, GLP2, GRPP
• Location: Chr.2:162142869-162152404 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GCG	NM_002054.4			NP_002045.1
	BC005278.1			AAH05278.1
	BM272442.1
	J04040.1			AAA52567.1

Target Gene Details

• Entrez Gene ID: 101929532
• Gene Name: uncharacterized LOC101929532
• Gene Aliases: -
• Location: Chr.2:162114441-162172739 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC101929532	NR_110255.1
	BX648358.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834440	Chr.2:162145758 - 162318828 on Build GRCh38	Gain	GCA LOC101929532 IFIH1 FAP GCG
nsv834439	Chr.2:162057118 - 162223456 on Build GRCh38	Gain	LOC101929532 FAP DPP4 GCG

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
feeding behavior
cell proliferation
protein kinase A signaling
positive regulation of peptidyl-threonine phosphorylation
positive regulation of cAMP biosynthetic process
positive regulation of protein binding
negative regulation of appetite
positive regulation of peptidyl-serine phosphorylation
positive regulation of insulin secretion involved in cellular response to glucose stimulus
positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
response to starvation
negative regulation of apoptotic process
positive regulation of protein kinase activity
regulation of insulin secretion
positive regulation of histone H3-K4 methylation
positive regulation of ERK1 and ERK2 cascade
cellular response to glucagon stimulus
positive regulation of calcium ion import
negative regulation of execution phase of apoptosis
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

receptor binding
hormone activity
protein binding
glucagon receptor binding
identical protein binding