Hs02886644_cn

• Gene Symbol: GRIN3B
• Assay Reference Genome Location: Chr.19:1007701 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 116444
• Gene Name: glutamate ionotropic receptor NMDA type subunit 3B
• Gene Aliases: GluN3B, NR3B
• Location: Chr.19:1000419-1009814 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRIN3B	NM_138690.2	4	2145	NP_619635.1
	XM_017026243.1	3	1391	XP_016881732.1
	AY507106.1	4	2145	AAS87020.1
	AY507107.1	4	2145	AAS87021.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	POLR2E GPX4 CBARP ARHGAP45 STK11 RNU6-9 WDR18 R3HDM4 RNU6-2 TMEM259 KISS1R CIRBP ATP5D MIDN CNN2 ARID3A ABCA7 C19orf24 CIRBP-AS1 LOC105372235 EFNA2 LOC102725180 SBNO2 GRIN3B
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	POLR2E CBARP STK11 RNU6-9 WDR18 MED16 CIRBP ATP5D MIDN CNN2 ARID3A ABCA7 C19orf24 EFNA2 SBNO2 GRIN3B GPX4 ARHGAP45 R3HDM4 RNU6-2 TMEM259 KISS1R CIRBP-AS1 LOC105372235 LOC102725180
nsv578188	Chr.19:923744 - 1059005 on Build GRCh38	Loss	TMEM259 CNN2 ARID3A ABCA7 WDR18 LOC105372235 RNU6-2 GRIN3B
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	TMEM259 POLR2E GPX4 CNN2 ARID3A ARHGAP45 ABCA7 WDR18 LOC105372235 RNU6-2 SBNO2 GRIN3B
esv2758743	Chr.19:951641 - 1544934 on Build GRCh38	Gain+Loss	POLR2E RPS15 CBARP STK11 WDR18 PCSK4 CIRBP DAZAP1 ATP5D MIDN CNN2 ARID3A ABCA7 C19orf24 ADAMTSL5 EFNA2 SBNO2 GRIN3B GPX4 ARHGAP45 NDUFS7 PLK5 RNU6-2 REEP6 TMEM259 C19orf25 APC2 GAMT CIRBP-AS1 LOC105372235 LOC102725180 MUM1
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	POLR2E POLRMT TPGS1 PLPPR3 PTBP1 RNU6-9 WDR18 BSG LOC101928450 MIR4745 CFD MED16 CNN2 ARID3A ABCA7 GZMM C2CD4C SHC2 GRIN3B ELANE PRTN3 GPX4 AZU1 ARHGAP45 FSTL3 MISP PRSS57 RNF126 HCN2 R3HDM4 RNU6-2 TMEM259 KISS1R THEG MADCAM1 PALM ODF3L2 FGF22 MIR3187 LOC105372235 CDC34
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	POLRMT TPGS1 PLPPR3 PTBP1 RNU6-9 WDR18 BSG LOC101928450 MIR4745 CFD MED16 ARID3A GZMM C2CD4C SHC2 GRIN3B ELANE PRTN3 AZU1 FSTL3 MISP PRSS57 RNF126 HCN2 R3HDM4 KISS1R MADCAM1 PALM ODF3L2 FGF22 MIR3187 LOC105372235 CDC34

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

ionotropic glutamate receptor signaling pathway
protein insertion into membrane
regulation of calcium ion transport
calcium ion transmembrane transport

Function(s)

NMDA glutamate receptor activity
extracellular-glutamate-gated ion channel activity
cation channel activity
calcium channel activity
glycine binding
neurotransmitter receptor activity
neurotransmitter binding