Hs02839290_cn

• Gene Symbol: NEUROD1
• Assay Reference Genome Location: Chr.2:181676885 on build GRCh38
• Cytoband: 2q31.3

Target Gene Details

• Entrez Gene ID: 4760
• Gene Name: neuronal differentiation 1
• Gene Aliases: BETA2, BHF-1, MODY6, NEUROD, bHLHa3
• Location: Chr.2:181676106-181680665 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NEUROD1	NM_002500.4	2	2223	NP_002491.2
	AB593068.1	2	2075
	AB593069.1	2	2077
	AB593070.1	2	2075
	AB593071.1	2	2075
	BM505034.1
	D82347.1	2	2085	BAA11558.1
	DN949274.1	1	430

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834477	Chr.2:181573394 - 181728800 on Build GRCh38	Gain	NEUROD1 CERKL

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

pancreatic A cell fate commitment
pancreatic PP cell fate commitment
transcription from RNA polymerase II promoter
nucleocytoplasmic transport
nitric oxide mediated signal transduction
response to glucose
anterior/posterior pattern specification
dentate gyrus development
cerebellum development
neurogenesis
signal transduction involved in regulation of gene expression
insulin secretion
endocrine pancreas development
amacrine cell differentiation
enteroendocrine cell differentiation
response to drug
glucose homeostasis
positive regulation of apoptotic process
positive regulation of cell differentiation
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of JAK-STAT cascade
embryonic organ morphogenesis
neuron development
inner ear development
regulation of insulin secretion
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of intestinal epithelial structure maintenance
regulation of cell cycle arrest
cellular response to glucose stimulus
negative regulation of type B pancreatic cell apoptotic process
positive regulation of transcription regulatory region DNA binding

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
RNA polymerase II transcription coactivator activity
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
sequence-specific DNA binding
protein heterodimerization activity
E-box binding