Hs02821504_cn

• Gene Symbol: FZD4
• Assay Reference Genome Location: Chr.11:86948626 on build GRCh38
• Cytoband: 11q14.2

Target Gene Details

• Entrez Gene ID: 8322
• Gene Name: frizzled class receptor 4
• Gene Aliases: CD344, EVR1, FEVR, FZD4S, Fz-4, Fz4, FzE4, GPCR, hFz4
• Location: Chr.11:86945675-86955398 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FZD4	NM_012193.3	2	4443	NP_036325.2
	AB032417.1	2	4436	BAA86286.1
	AK025516.1	1	216
	AK025791.1	1	692

Target Gene Details

• Entrez Gene ID: 11098
• Gene Name: protease, serine 23
• Gene Aliases: SIG13, SPUVE, ZSIG13
• Location: Chr.11:86791059-86952910 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRSS23	NR_120591.1
	NR_120592.1
	AU279649.1
	DA396057.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3627099	Chr.11:86660723 - 87045565 on Build GRCh38	Gain	PRSS23 OR7E13P ME3 OR7E2P LOC100506368 TMEM135 FZD4

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

vasculogenesis
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
sensory perception of sound
negative regulation of cell-substrate adhesion
Wnt signaling pathway
neuron differentiation
regulation of vascular endothelial growth factor receptor signaling pathway
locomotion involved in locomotory behavior
substrate adhesion-dependent cell spreading
extracellular matrix-cell signaling
progesterone secretion
positive regulation of JUN kinase activity
positive regulation of transcription, DNA-templated
positive regulation of sequence-specific DNA binding transcription factor activity
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
retina vasculature morphogenesis in camera-type eye
cerebellum vasculature morphogenesis
retinal blood vessel morphogenesis
cellular response to retinoic acid
proteolysis

Function(s)

G-protein coupled receptor activity
protein binding
Wnt-protein binding
cytokine binding
PDZ domain binding
ubiquitin protein ligase binding
protein homodimerization activity
Wnt-activated receptor activity
protein heterodimerization activity
serine-type endopeptidase activity