Hs02736239_cn

• Gene Symbol: CDT1
• Assay Reference Genome Location: Chr.16:88806605 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 81620
• Gene Name: chromatin licensing and DNA replication factor 1
• Gene Aliases: DUP, RIS2
• Location: Chr.16:88803778-88809258 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDT1	NM_030928.3	7	1107	NP_112190.2
	AB053172.1	7	1107	BAB61878.1
	AF070552.1	5	646
	AF321125.1	7	1078	AAG45181.1
	BC000137.2	7	1069	AAH00137.2
	BC008676.1	7	945	AAH08676.1
	BC008860.2	7	1000	AAH08860.2
	BC009410.1	7	1063	AAH09410.1
	BC014202.2	3	368	AAH14202.2
	BC021126.1	5	639
	BC049205.1	5	711	AAH49205.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	ZNF778 PABPN1L LOC101927793 MIR4722 CBFA2T3 APRT ACSF3 LOC107987238 LOC105371409 SLC22A31 GALNS LOC100129697 LOC339059 LINC00304 CTU2 LOC100289580 CDT1 CDH15 LOC400558 TRAPPC2L PIEZO1
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	PABPN1L LOC101927793 CBFA2T3 APRT ACSF3 LOC107987238 LOC105371409 SLC22A31 GALNS LOC100129697 LINC00304 CDT1 CDH15 LOC400558 TRAPPC2L
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	RNF166 GALNS MIR4722 LOC339059 CTU2 LOC100289580 APRT SNAI3 CDT1 SNAI3-AS1 LOC107987238 PIEZO1
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	ZNF778 PABPN1L LOC101927793 CBFA2T3 LOC105371414 APRT ACSF3 LOC107987238 LOC105371409 SLC22A31 GALNS LOC100129697 LOC339059 LINC00304 LOC100289580 LOC100287036 CDT1 ANKRD11 CDH15 LOC400558 TRAPPC2L PIEZO1
nsv471117	Chr.16:88805821 - 88838392 on Build GRCh38	Gain	GALNS APRT CDT1 LOC107987238
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	PABPN1L LOC105371409 LOC101927793 GALNS LOC100129697 CBFA2T3 APRT CDT1 LOC107987238 TRAPPC2L
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	PABPN1L MIR4722 CHMP1A FANCA CTU2 LOC100289580 SNAI3-AS1 ANKRD11 TRAPPC2L VPS9D1-AS1 CPNE7 LOC105371414 MC1R DEF8 APRT AFG3L1P LOC107987238 SPIRE2 VPS9D1 DBNDD1 SLC22A31 PRDM7 TUBB3 LOC339059 CENPBD1 CDK10 FAM157C LOC101927817 IL17C CDH15 CYBA LOC400558 ZNF778 SNORD68 LOC101927793 SNAI3 DPEP1 LOC105371409 RNF166 LOC100129697 LINC00304 TUBB8P7 RPL13 LOC100287036 CDT1 LOC105371419 PIEZO1 ZNF276 TCF25 CBFA2T3 LOC107984817 GAS8 GAS8-AS1 ACSF3 SPATA33 URAHP SPG7 GALNS MVD SPATA2L
nsv1063441	Chr.16:88767066 - 88861882 on Build GRCh38	Loss	GALNS APRT CDT1 LOC107987238 TRAPPC2L PIEZO1
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	PABPN1L LOC105371409 LOC101927793 GALNS LOC100129697 CBFA2T3 APRT CDT1 LOC107987238 TRAPPC2L PIEZO1
dgv5319n54	Chr.16:88804814 - 88809520 on Build GRCh38	Loss	APRT CDT1
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	PABPN1L LOC101927793 GALNS CBFA2T3 APRT CDT1 LOC107987238 TRAPPC2L PIEZO1
nsv573712	Chr.16:88796728 - 88809084 on Build GRCh38	Loss	CDT1
dgv3065n100	Chr.16:88711587 - 88927172 on Build GRCh38	Gain	PABPN1L LOC101927793 MIR4722 CBFA2T3 APRT LOC107987238 GALNS LOC339059 CTU2 LOC100289580 CDT1 TRAPPC2L PIEZO1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
regulation of DNA-dependent DNA replication initiation
regulation of nuclear cell cycle DNA replication

Function(s)

DNA binding
protein binding