Hs02733629_cn

• Gene Symbol: HELB
• Assay Reference Genome Location: Chr.12:66304830 on build GRCh38
• Cytoband: 12q14.3

Target Gene Details

• Entrez Gene ID: 92797
• Gene Name: DNA helicase B
• Gene Aliases: DHB, hDHB
• Location: Chr.12:66302545-66343643 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HELB	NM_033647.4	2	346	NP_387467.2
	NR_135080.1	2	346
	NR_135081.1	2	346
	XM_005269234.2	2	324	XP_005269291.1
	XM_017020230.1	2	324	XP_016875719.1
	AA070301.1	2	315
	AF319995.1	2	287	AAM73554.1
	AK290894.1	2	311
	DN997712.1	2	355

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3892212	Chr.12:66302630 - 66471921 on Build GRCh38	Loss	GRIP1 HELB
esv3629801	Chr.12:66277937 - 66308122 on Build GRCh38	Gain	HELB

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA helicase

Gene Ontology Categories:

Process(es)

mRNA splicing, via spliceosome
DNA replication
DNA replication, synthesis of RNA primer
DNA repair
cellular response to DNA damage stimulus
DNA duplex unwinding
regulation of DNA double-strand break processing
negative regulation of double-strand break repair via homologous recombination

Function(s)

ATP-dependent RNA helicase activity
ATP binding
single-stranded DNA-dependent ATP-dependent DNA helicase activity
ATP-dependent 5'-3' DNA helicase activity
poly(A) RNA binding