Hs02606464_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143992771 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1	7	1324	NP_000828.1
	NM_001009184.1	7	1212	NP_001009184.1
	AB097026.1	7	1136	BAC77379.1
	AK127640.1	7	1360
	AK294127.1	8	1069
	AL157442.1	1	55	CAB75662.3
	BC041788.1	7	1170	AAH41788.2
	BC084553.1	6	1061	AAH84553.1
	U44954.1	4	395	AAB94292.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	GRINA PARP10 PLEC
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	MIR6848 EXOSC4 CYC1 MAF1 VPS28 MIR6847 BOP1 GRINA LOC101928902 CPSF1 MIR6849 SCX KIFC2 MIR1234 MIR6846 WDR97 ADCK5 LRRC14 MIR661 SLC39A4 DGAT1 PARP10 FOXH1 MROH1 SMPD5 SPATC1 SLC52A2 TONSL-AS1 GPAA1 RECQL4 GPT LOC101928953 SHARPIN TONSL MIR7112 CYHR1 PPP1R16A OPLAH MIR939 MFSD3 HGH1 MIR6893 SCRT1 HSF1 PLEC TMEM249 FBXL6
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	MIR6848 EXOSC4 CYC1 MAF1 VPS28 MIR6847 BOP1 GRINA LOC101928902 CPSF1 MIR6849 SCX KIFC2 MIR1234 MIR6846 WDR97 ADCK5 LRRC14 MIR661 SLC39A4 DGAT1 PARP10 FOXH1 MROH1 SMPD5 SPATC1 SLC52A2 TONSL-AS1 GPAA1 RECQL4 GPT LOC101928953 SHARPIN TONSL MIR7112 CYHR1 PPP1R16A OPLAH MIR939 MFSD3 HGH1 MIR6893 SCRT1 HSF1 PLEC TMEM249 FBXL6
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	PARP10 EXOSC4 SMPD5 SPATC1 CYC1 GPAA1 MAF1 MIR6847 SHARPIN GRINA OPLAH MIR6846 PLEC WDR97
dgv12431n54	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	EPPK1 MIR661 PARP10 MROH1 EXOSC4 SMPD5 SPATC1 CYC1 GPAA1 MAF1 MIR6847 SHARPIN GRINA OPLAH HGH1 MIR6846 PLEC WDR97
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	EPPK1 MIR661 PARP10 EXOSC4 SMPD5 SPATC1 CYC1 GPAA1 MAF1 MIR6847 SHARPIN GRINA OPLAH MIR6846 PLEC WDR97
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	EPPK1 MIR661 MIR937 PARP10 LOC642574 NRBP2 EXOSC4 SMPD5 SPATC1 SCRIB MIR6847 PUF60 GRINA MIR6845 OPLAH MIR6846 PLEC
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	GRINA MIR661 PARP10 EXOSC4 OPLAH SMPD5 SPATC1 CYC1 GPAA1 MIR6846 PLEC MIR6847
dgv12433n54	Chr.8:143902404 - 144120626 on Build GRCh38	Gain	MIR661 PARP10 EXOSC4 SMPD5 SPATC1 CYC1 GPAA1 MAF1 MIR6847 SHARPIN GRINA OPLAH MIR6846 PLEC WDR97
nsv612906	Chr.8:143917935 - 144090784 on Build GRCh38	Loss	GRINA MIR661 PARP10 EXOSC4 OPLAH SMPD5 SPATC1 GPAA1 MIR6846 PLEC MIR6847

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding