Hs02390553_cn

• Gene Symbol: KLHL10
• Assay Reference Genome Location: Chr.17:41835937 on build GRCh38
• Cytoband: 17q21.2

Target Gene Details

• Entrez Gene ID: 317719
• Gene Name: kelch like family member 10
• Gene Aliases: SPGF11
• Location: Chr.17:41835685-41848347 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLHL10	XM_011524706.2			XP_011523008.1

Target Gene Details

• Entrez Gene ID: 115024
• Gene Name: 5'-nucleotidase, cytosolic IIIB
• Gene Aliases: NT5C3L, cN-IIIB
• Location: Chr.17:41825082-41836276 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NT5C3B	NM_052935.4			NP_443167.4
	NR_033464.1
	NR_033465.1	1	335
	XM_006721669.3			XP_006721732.1
	XM_006721670.3			XP_006721733.1
	XM_011524276.2			XP_011522578.1
	XM_011524277.2			XP_011522579.1
	XM_017024127.1			XP_016879616.1
	BC013742.1	1	156	AAH13742.2
	BC014132.2	1	259	AAH14132.2
	BC016971.1	1	280	AAH16971.2
	BC067788.1	1	269	AAH67788.1
	BE296438.1	1	232
	BI914049.1
	BI917511.1	1	338
	BX365588.2
	BX438861.2	1	303
	BX460247.2	1	293
	CN393115.1
	DR159341.1	1	286

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv3174n100	Chr.17:41778258 - 41843183 on Build GRCh38	Gain	NT5C3B KLHL10 FKBP10 JUP P3H4
nsv827994	Chr.17:41823755 - 41836053 on Build GRCh38	Gain	NT5C3B KLHL10
nsv1057008	Chr.17:41832887 - 41885423 on Build GRCh38	Gain	NT5C3B KLHL10 KLHL11 ACLY
nsv833447	Chr.17:41794279 - 41955275 on Build GRCh38	Loss	NT5C3B KLHL10 FKBP10 KLHL11 ACLY P3H4 TTC25

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein, esterase, hydrolase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

cell morphogenesis
spermatid development
male gonad development
fertilization
protein ubiquitination
male genitalia morphogenesis
homeostasis of number of cells within a tissue
nucleotide metabolic process
dephosphorylation
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay

Function(s)

ubiquitin-protein transferase activity
nucleotide binding
magnesium ion binding
protein binding
5'-nucleotidase activity