Hs02327954_cn

• Gene Symbol: SEMA3F
• Assay Reference Genome Location: Chr.3:50174086 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 6405
• Gene Name: semaphorin 3F
• Gene Aliases: SEMA-IV, SEMA4, SEMAK
• Location: Chr.3:50155045-50189075 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA3F	NM_001318798.1			NP_001305727.1
	NM_001318800.1			NP_001305729.1
	NM_004186.4			NP_004177.3
	XM_005265381.4			XP_005265438.1
	XM_005265382.4			XP_005265439.1
	XM_006713290.3			XP_006713353.1
	XM_011533998.2			XP_011532300.1
	XM_011534000.2			XP_011532302.1
	AB209259.1			BAD92496.1
	BC042914.1			AAH42914.1
	BF058597.1
	BQ949723.1
	U33920.1			AAC50568.1
	U38276.1			AAB18276.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759148	Chr.3:50161045 - 50333946 on Build GRCh38	Loss	GNAT1 GNAI2 MIR6872 NAT6 HYAL2 TUSC2 IFRD2 MIR566 HYAL3 SLC38A3 RASSF1 HYAL1 SEMA3B LSMEM2 MIR5787 SEMA3F SEMA3B-AS1
nsv523560	Chr.3:50134964 - 50314769 on Build GRCh38	Loss	GNAT1 GNAI2 MIR6872 NAT6 LOC107986035 IFRD2 MIR566 HYAL3 SLC38A3 HYAL1 SEMA3B LSMEM2 MIR5787 SEMA3F SEMA3B-AS1 SEMA3F-AS1
dgv602n27	Chr.3:50140578 - 50287241 on Build GRCh38	Loss	MIR566 GNAT1 SLC38A3 GNAI2 SEMA3B MIR6872 LSMEM2 LOC107986035 MIR5787 SEMA3F SEMA3B-AS1 SEMA3F-AS1
nsv834692	Chr.3:50161052 - 50356033 on Build GRCh38	Loss	GNAT1 GNAI2 MIR6872 NAT6 TMEM115 HYAL2 TUSC2 RASSF1-AS1 ZMYND10 IFRD2 MIR566 HYAL3 SLC38A3 RASSF1 HYAL1 NPRL2 SEMA3B LSMEM2 MIR5787 SEMA3F SEMA3B-AS1 CYB561D2
dgv8316n54	Chr.3:50115923 - 50299991 on Build GRCh38	Loss	GNAT1 GNAI2 MIR6872 NAT6 LOC107986035 IFRD2 RBM5 MIR566 HYAL3 SLC38A3 HYAL1 SEMA3B LSMEM2 MIR5787 SEMA3F SEMA3B-AS1 SEMA3F-AS1
nsv515986	Chr.3:50066874 - 50254353 on Build GRCh38	Loss	MIR566 GNAT1 SLC38A3 GNAI2 RBM6 LOC107986035 RBM5-AS1 MIR5787 SEMA3F SEMA3F-AS1 RBM5
nsv470561	Chr.3:50121341 - 50547568 on Build GRCh38	Loss	GNAT1 GNAI2 MIR6872 NAT6 TMEM115 LOC107986035 RASSF1-AS1 IFRD2 MIR566 HYAL3 SLC38A3 NPRL2 MIR5787 SEMA3F SEMA3B-AS1 CYB561D2 CACNA2D2 HYAL2 TUSC2 ZMYND10 RASSF1 HYAL1 SEMA3B LSMEM2 SEMA3F-AS1
nsv523662	Chr.3:50107518 - 50547568 on Build GRCh38	Loss	GNAT1 GNAI2 MIR6872 NAT6 TMEM115 LOC107986035 RASSF1-AS1 IFRD2 MIR566 HYAL3 SLC38A3 NPRL2 MIR5787 SEMA3F SEMA3B-AS1 CYB561D2 CACNA2D2 HYAL2 TUSC2 ZMYND10 RBM5 RASSF1 HYAL1 SEMA3B LSMEM2 SEMA3F-AS1
nsv834690	Chr.3:50064402 - 50263192 on Build GRCh38	Loss	MIR566 GNAT1 SLC38A3 GNAI2 RBM6 LOC107986035 RBM5-AS1 MIR5787 SEMA3F SEMA3F-AS1 RBM5
nsv954855	Chr.3:50152468 - 50439169 on Build GRCh38	Deletion	GNAT1 GNAI2 MIR6872 NAT6 TMEM115 LOC107986035 RASSF1-AS1 IFRD2 MIR566 HYAL3 SLC38A3 NPRL2 MIR5787 SEMA3F SEMA3B-AS1 CYB561D2 CACNA2D2 HYAL2 TUSC2 ZMYND10 RASSF1 HYAL1 SEMA3B LSMEM2 SEMA3F-AS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
axon guidance
facial nerve structural organization
trigeminal nerve structural organization
nerve development
branchiomotor neuron axon guidance
positive regulation of cell migration
ventral trunk neural crest cell migration
negative regulation of axon extension involved in axon guidance
axon extension involved in axon guidance
negative chemotaxis
sympathetic ganglion development
semaphorin-plexin signaling pathway
sympathetic neuron projection extension
sympathetic neuron projection guidance
neural crest cell migration involved in autonomic nervous system development
semaphorin-plexin signaling pathway involved in neuron projection guidance
semaphorin-plexin signaling pathway involved in axon guidance

Function(s)

semaphorin receptor binding
neuropilin binding
chemorepellent activity