Hs02286981_cn

• Gene Symbol: HELZ2
• Assay Reference Genome Location: Chr.20:63558237 on build GRCh38
• Cytoband: 20q13.33

Target Gene Details

• Entrez Gene ID: 85441
• Gene Name: helicase with zinc finger 2
• Gene Aliases: PDIP-1, PRIC285
• Location: Chr.20:63558086-63574239 on Build GRCh38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HELZ2	NM_001037335.2	20	9851	NP_001032412.2
	NM_033405.3	14	7356	NP_208384.3
	AB051556.2	14	7356
	AF517673.1	14	7676	AAM74197.1
	AK074171.1	12	4385	BAB84997.1
	BC150283.1	14	7356
	BQ707207.1	1	450

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv953306	Chr.20:63151949 - 63571247 on Build GRCh38	Deletion	FNDC11 LOC107985425 LOC102723788 BIRC7 COL20A1 PTK6 CHRNA4 HELZ2 EEF1A2 LOC100130587 PPDPF FLJ16779 LOC100130152 SRMS MIR3196 MIR124-3 ARFGAP1 KCNQ2 YTHDF1 MIR4326 NKAIN4
nsv586573	Chr.20:63535645 - 63560584 on Build GRCh38	Loss	HELZ2 FNDC11 SRMS PTK6
nsv521734	Chr.20:63522433 - 63566995 on Build GRCh38	Loss	HELZ2 FNDC11 SRMS PTK6
nsv9825	Chr.20:62775470 - 63601330 on Build GRCh38	Gain	TCFL5 DPH3P1 LOC107985425 LOC102723788 BIRC7 OGFR-AS1 HAR1A MRGBP GMEB2 COL9A3 HAR1B COL20A1 OGFR PPDPF FLJ16779 LOC100130152 LINC01056 MIR3196 MIR124-3 ARFGAP1 YTHDF1 NKAIN4 GID8 BHLHE23 FNDC11 LINC00659 SLC17A9 LOC107985428 DIDO1 PTK6 CHRNA4 HELZ2 EEF1A2 LOC100130587 SRMS LINC00029 KCNQ2 LOC63930 MIR4326
nsv470563	Chr.20:63486715 - 63793308 on Build GRCh38	Loss	FNDC11 ARFRP1 LIME1 GMEB2 RTEL1 PTK6 HELZ2 EEF1A2 PPDPF STMN3 SRMS SLC2A4RG LOC100505771 ZBTB46 ZGPAT RTEL1-TNFRSF6B TNFRSF6B
nsv834034	Chr.20:63462825 - 63625901 on Build GRCh38	Loss	HELZ2 EEF1A2 PPDPF FNDC11 SRMS GMEB2 KCNQ2 PTK6
nsv517702	Chr.20:63540916 - 63581575 on Build GRCh38	Loss	HELZ2 FNDC11 SRMS
esv2758806	Chr.20:63470996 - 63745014 on Build GRCh38	Gain+Loss	FNDC11 ARFRP1 LIME1 GMEB2 RTEL1 PTK6 HELZ2 EEF1A2 PPDPF STMN3 SRMS SLC2A4RG LOC100505771 ZBTB46 KCNQ2 ZGPAT RTEL1-TNFRSF6B TNFRSF6B

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
cellular lipid metabolic process
positive regulation of transcription from RNA polymerase II promoter

Function(s)

DNA binding
helicase activity
protein binding
ATP binding
ligand-dependent nuclear receptor transcription coactivator activity
poly(A) RNA binding
metal ion binding