Hs02212093_cn

• Gene Symbol: KLRG1
• Assay Reference Genome Location: Chr.12:9166209 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10219
• Gene Name: killer cell lectin like receptor G1
• Gene Aliases: 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
• Location: Chr.12:8989079-9255692 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRG1	XM_017018685.1			XP_016874174.1

Target Gene Details

• Entrez Gene ID: 5858
• Gene Name: PZP, alpha-2-macroglobulin like
• Gene Aliases: CPAMD6
• Location: Chr.12:9140730-9208370 on Build GRCh38
• Assay Gene Location: Overlaps Intron 16 - Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PZP	NM_002864.2			NP_002855.2
	XM_011520804.2			XP_011519106.1
	XM_011520805.2			XP_011519107.1
	XM_011520806.1			XP_011519108.1
	XM_011520807.2			XP_011519109.1
	XM_017019763.1			XP_016875252.1
	XM_017019764.1			XP_016875253.1
	XM_017019765.1			XP_016875254.1
	XM_017019766.1			XP_016875255.1
	XM_017019767.1			XP_016875256.1
	AK302259.1
	AK308724.1
	AK313639.1
	BC111756.1			AAI11757.1
	DB040351.1
	X54380.1			CAA38255.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv523958	Chr.12:9150844 - 9396476 on Build GRCh38	Loss	LOC642846 MIR1244-3 LOC101930452 PZP LOC105369649 LOC101928030 A2MP1 LINC00987 KLRG1
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	CLEC2D LOC400002 LOC374443 LOC101930452 KLRF1 CLEC4E A2MP1 CLECL1 CLEC4D KLRG1 LOC642846 M6PR LOC728715 LOC100506159 OVOS LINC00612 CLEC6A LOC105369728 A2M MIR1244-3 CLEC12A RIMKLB A2ML1 AICDA KLRB1 LOC105376678 KLRF2 CLEC2B LOC105369649 DDX12P CLEC2A CD69 PHC1 A2M-AS1 PZP MFAP5 LOC101928030 LINC00987
nsv527404	Chr.12:9098005 - 9282648 on Build GRCh38	Gain	A2M MIR1244-3 PZP A2MP1 LINC00987 KLRG1
nsv557355	Chr.12:9157399 - 9376419 on Build GRCh38	Gain	LOC642846 MIR1244-3 LOC101930452 PZP LOC105369649 LOC101928030 A2MP1 LINC00987 KLRG1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor, protease inhibitor

Gene Ontology Categories:

Process(es)

inflammatory response
cellular defense response
cell surface receptor signaling pathway
innate immune response
female pregnancy
negative regulation of endopeptidase activity

Function(s)

receptor activity
protein binding
carbohydrate binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity