Hs01987154_cn

• Gene Symbol: ZNF281
• Assay Reference Genome Location: Chr.1:200409002 on build GRCh38
• Cytoband: 1q32.1

Target Gene Details

• Entrez Gene ID: 23528
• Gene Name: zinc finger protein 281
• Gene Aliases: ZBP-99, ZNP-99
• Location: Chr.1:200404947-200483604 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF281	NM_001281293.1	2	835	NP_001268222.1
	NM_001281294.1	3	727	NP_001268223.1
	NM_012482.4	2	831	NP_036614.1
	XM_017000887.1	5	2216	XP_016856376.1
	XM_017000888.1	5	1174	XP_016856377.1
	AF125158.1	1	727	AAD21084.1
	AJ132591.1	1	248	CAB70967.1
	AJ132592.1	2	811	CAB70968.1
	AK022916.1	2	762
	AK027284.1	2	829
	AK094701.1	3	662
	AK297233.1	3	685
	BC051905.1	1	720	AAH51905.1
	BC060820.1	2	811	AAH60820.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv548990	Chr.1:200400630 - 200452338 on Build GRCh38	Loss	ZNF281

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
embryonic body morphogenesis
negative regulation of gene expression
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
stem cell differentiation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding