Hs01936252_cn

• Gene Symbol: SEMA3F
• Assay Reference Genome Location: Chr.3:50173914 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 6405
• Gene Name: semaphorin 3F
• Gene Aliases: SEMA-IV, SEMA4, SEMAK
• Location: Chr.3:50155045-50189075 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA3F	NM_001318798.1	3	268	NP_001305727.1
	NM_001318800.1	3	552	NP_001305729.1
	NM_004186.4	3	436	NP_004177.3
	XM_005265381.4	3	566	XP_005265438.1
	XM_005265382.4	3	369	XP_005265439.1
	XM_006713290.3	3	369	XP_006713353.1
	XM_011533998.2	3	368	XP_011532300.1
	XM_011534000.2	3	369	XP_011532302.1
	AB209259.1	3	222	BAD92496.1
	BC042914.1	3	432	AAH42914.1
	BF058597.1	3	436
	BQ949723.1	3	377
	U33920.1	2	312	AAC50568.1
	U38276.1	3	549	AAB18276.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759148	Chr.3:50161045 - 50333946 on Build GRCh38	Loss	TUSC2 MIR6872 HYAL3 SEMA3B MIR5787 SEMA3B-AS1 SLC38A3 MIR566 GNAT1 RASSF1 HYAL2 NAT6 HYAL1 IFRD2 SEMA3F LSMEM2 GNAI2
nsv523560	Chr.3:50134964 - 50314769 on Build GRCh38	Loss	MIR6872 HYAL3 SEMA3B MIR5787 SEMA3B-AS1 SLC38A3 MIR566 GNAT1 NAT6 HYAL1 LOC107986035 IFRD2 SEMA3F-AS1 SEMA3F LSMEM2 GNAI2
dgv602n27	Chr.3:50140578 - 50287241 on Build GRCh38	Loss	MIR6872 SEMA3B MIR5787 SEMA3B-AS1 SLC38A3 LOC107986035 MIR566 GNAT1 SEMA3F-AS1 SEMA3F LSMEM2 GNAI2
nsv834692	Chr.3:50161052 - 50356033 on Build GRCh38	Loss	TUSC2 MIR6872 NPRL2 HYAL3 ZMYND10 SEMA3B MIR5787 SEMA3B-AS1 SLC38A3 MIR566 GNAT1 TMEM115 RASSF1 HYAL2 NAT6 HYAL1 CYB561D2 RASSF1-AS1 IFRD2 SEMA3F LSMEM2 GNAI2
dgv8316n54	Chr.3:50115923 - 50299991 on Build GRCh38	Loss	MIR6872 HYAL3 SEMA3B MIR5787 SEMA3B-AS1 SLC38A3 RBM5 MIR566 GNAT1 NAT6 HYAL1 LOC107986035 IFRD2 SEMA3F-AS1 SEMA3F LSMEM2 GNAI2
nsv515986	Chr.3:50066874 - 50254353 on Build GRCh38	Loss	RBM5-AS1 MIR5787 SLC38A3 RBM5 LOC107986035 MIR566 RBM6 GNAT1 SEMA3F-AS1 SEMA3F GNAI2
nsv470561	Chr.3:50121341 - 50547568 on Build GRCh38	Loss	ZMYND10 SEMA3B SEMA3B-AS1 RASSF1 IFRD2 SEMA3F-AS1 SEMA3F LSMEM2 GNAI2 TUSC2 MIR6872 NPRL2 HYAL3 MIR5787 SLC38A3 MIR566 GNAT1 TMEM115 HYAL2 NAT6 HYAL1 CACNA2D2 CYB561D2 RASSF1-AS1 LOC107986035
nsv523662	Chr.3:50107518 - 50547568 on Build GRCh38	Loss	ZMYND10 SEMA3B SEMA3B-AS1 RBM5 RASSF1 IFRD2 SEMA3F-AS1 SEMA3F LSMEM2 GNAI2 TUSC2 MIR6872 NPRL2 HYAL3 MIR5787 SLC38A3 MIR566 GNAT1 TMEM115 HYAL2 NAT6 HYAL1 CACNA2D2 CYB561D2 RASSF1-AS1 LOC107986035
nsv834690	Chr.3:50064402 - 50263192 on Build GRCh38	Loss	RBM5-AS1 MIR5787 SLC38A3 RBM5 LOC107986035 MIR566 RBM6 GNAT1 SEMA3F-AS1 SEMA3F GNAI2
nsv954855	Chr.3:50152468 - 50439169 on Build GRCh38	Deletion	ZMYND10 SEMA3B SEMA3B-AS1 RASSF1 IFRD2 SEMA3F-AS1 SEMA3F LSMEM2 GNAI2 TUSC2 MIR6872 NPRL2 HYAL3 MIR5787 SLC38A3 MIR566 GNAT1 TMEM115 HYAL2 NAT6 HYAL1 CACNA2D2 CYB561D2 RASSF1-AS1 LOC107986035

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
axon guidance
facial nerve structural organization
trigeminal nerve structural organization
nerve development
branchiomotor neuron axon guidance
positive regulation of cell migration
ventral trunk neural crest cell migration
negative regulation of axon extension involved in axon guidance
axon extension involved in axon guidance
negative chemotaxis
sympathetic ganglion development
semaphorin-plexin signaling pathway
sympathetic neuron projection extension
sympathetic neuron projection guidance
neural crest cell migration involved in autonomic nervous system development
semaphorin-plexin signaling pathway involved in neuron projection guidance
semaphorin-plexin signaling pathway involved in axon guidance

Function(s)

semaphorin receptor binding
neuropilin binding
chemorepellent activity