Hs01917000_cn

• Gene Symbol: KLRG1
• Assay Reference Genome Location: Chr.12:9163717 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10219
• Gene Name: killer cell lectin like receptor G1
• Gene Aliases: 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
• Location: Chr.12:8989079-9255692 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRG1	XM_017018685.1			XP_016874174.1

Target Gene Details

• Entrez Gene ID: 5858
• Gene Name: PZP, alpha-2-macroglobulin like
• Gene Aliases: CPAMD6
• Location: Chr.12:9140730-9208370 on Build GRCh38
• Assay Gene Location: Overlaps Intron 20 - Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PZP	NM_002864.2			NP_002855.2
	XM_011520804.2			XP_011519106.1
	XM_011520805.2			XP_011519107.1
	XM_011520806.1			XP_011519108.1
	XM_011520807.2			XP_011519109.1
	XM_017019763.1			XP_016875252.1
	XM_017019764.1			XP_016875253.1
	XM_017019765.1			XP_016875254.1
	XM_017019766.1			XP_016875255.1
	XM_017019767.1			XP_016875256.1
	AK302259.1
	AK308724.1
	AK313639.1
	BC111756.1			AAI11757.1
	DB040351.1
	X54380.1			CAA38255.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv523958	Chr.12:9150844 - 9396476 on Build GRCh38	Loss	LOC642846 PZP KLRG1 LOC105369649 MIR1244-3 A2MP1 LINC00987 LOC101930452 LOC101928030
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	LOC105369649 LINC00987 LOC101930452 LINC00612 KLRF1 CLEC4D LOC642846 PZP CLEC6A RIMKLB AICDA OVOS A2M LOC100506159 CLEC4E M6PR A2MP1 A2ML1 LOC105376678 LOC400002 CD69 MFAP5 LOC374443 CLEC2D CLEC2A KLRF2 DDX12P LOC728715 KLRG1 PHC1 LOC105369728 A2M-AS1 KLRB1 MIR1244-3 CLECL1 LOC101928030 CLEC12A CLEC2B
nsv527404	Chr.12:9098005 - 9282648 on Build GRCh38	Gain	PZP KLRG1 A2M MIR1244-3 A2MP1 LINC00987
nsv557355	Chr.12:9157399 - 9376419 on Build GRCh38	Gain	LOC642846 PZP KLRG1 LOC105369649 MIR1244-3 A2MP1 LINC00987 LOC101930452 LOC101928030

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor, protease inhibitor

Gene Ontology Categories:

Process(es)

inflammatory response
cellular defense response
cell surface receptor signaling pathway
innate immune response
female pregnancy
negative regulation of endopeptidase activity

Function(s)

receptor activity
protein binding
carbohydrate binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity