Hs01774270_cn

• Gene Symbol: C10orf2
• Assay Reference Genome Location: Chr.10:100987944 on build GRCh38
• Cytoband: 10q24.31

Target Gene Details

• Entrez Gene ID: 56652
• Gene Name: chromosome 10 open reading frame 2
• Gene Aliases: ATXN8, IOSCA, MTDPS7, PEO, PEO1, PEOA3, PRLTS5, SANDO, SCA8, TWINL
• Location: Chr.10:100987527-100994403 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
C10orf2	NM_001163812.1	1	409	NP_001157284.1
	NM_001163813.1			NP_001157285.1
	NM_001163814.1			NP_001157286.1
	NM_021830.4	1	409	NP_068602.2
	XM_011539975.2			XP_011538277.1
	AK297068.1
	AK308098.1	1	409
	BQ643363.1
	BX640829.1	1	391	CAE45905.1
	CB112401.1
	DB090322.1	1	408

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831965	Chr.10:100916724 - 101082796 on Build GRCh38	Loss	LZTS2 SLF2 SFXN3 PDZD7 SEMA4G C10orf2 MIR608 MRPL43 KAZALD1
nsv517698	Chr.10:100965896 - 101017113 on Build GRCh38	Loss	LZTS2 PDZD7 SEMA4G C10orf2 MIR608 MRPL43
nsv467443	Chr.10:100929460 - 101007360 on Build GRCh38	Loss	LZTS2 SLF2 SEMA4G C10orf2 MIR608 MRPL43

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

mitochondrial DNA replication
DNA unwinding involved in DNA replication
transcription from mitochondrial promoter
mitochondrion organization
protein hexamerization
protein homooligomerization
cellular response to glucose stimulus

Function(s)

protease binding
single-stranded DNA binding
ATP binding
5'-3' DNA helicase activity