Hs01665379_cn

• Gene Symbol: RAC2
• Assay Reference Genome Location: Chr.22:37244166 on build GRCh38
• Cytoband: 22q13.1

Target Gene Details

• Entrez Gene ID: 5880
• Gene Name: ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
• Gene Aliases: EN-7, Gx, HSPC022, p21-Rac2
• Location: Chr.22:37225261-37244299 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RAC2	NM_002872.4	1	134	NP_002863.1
	XM_006724286.3	1	94	XP_006724349.1
	AF498965.1			AAM21112.1
	AK096924.1	1	94
	BC001485.2	1	106	AAH01485.1
	BI908751.1	1	134
	BQ934070.1	1	102
	BT006919.1			AAP35565.1
	CR456555.1			CAG30441.1
	M29871.1			AAA36538.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834188	Chr.22:37210658 - 37396179 on Build GRCh38	Loss	CYTH4 RAC2 SSTR3 ELFN2 LOC100506271
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	C1QTNF6 GGA1 CDC42EP1 LGALS2 TST LOC101927051 TRIOBP NOL12 SSTR3 ELFN2 CARD10 LOC102724378 TMPRSS6 KCTD17 MFNG CYTH4 RAC2 PDXP SH3BP1 MPST LGALS1 LOC100506271 TEX33 IL2RB
nsv528767	Chr.22:37242920 - 37254804 on Build GRCh38	Gain	RAC2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

small GTPase

Gene Ontology Categories:

Process(es)

chemotaxis
actin filament organization
signal transduction
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
positive regulation of cell proliferation
regulation of hydrogen peroxide metabolic process
positive regulation of lamellipodium assembly
regulation of cell-substrate adhesion
cell projection assembly
platelet activation
regulation of T cell proliferation
regulation of mast cell degranulation
bone resorption
regulation of protein kinase activity
regulation of small GTPase mediated signal transduction
regulation of respiratory burst
regulation of mast cell chemotaxis
lymphocyte aggregation
positive regulation of neutrophil chemotaxis
regulation of neutrophil migration
positive regulation of protein targeting to mitochondrion

Function(s)

GTPase activity
GTP binding
protein kinase regulator activity