Hs01555447_cn

• Gene Symbol: SEMA4F
• Assay Reference Genome Location: Chr.2:74662750 on build GRCh38
• Cytoband: 2p13.1

Target Gene Details

• Entrez Gene ID: 10505
• Gene Name: ssemaphorin 4F
• Gene Aliases: M-SEMA, PRO2353, S4F, SEMAM, SEMAW, m-Sema-M
• Location: Chr.2:74654228-74699013 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA4F	NM_001271661.1			NP_001258590.1
	NM_001271662.1			NP_001258591.1
	NM_004263.4			NP_004254.2
	NR_073398.1
	NR_073399.1
	XM_011532475.2			XP_011530777.1
	XM_011532476.2			XP_011530778.1
	XM_011532477.2			XP_011530779.1
	XM_017003172.1			XP_016858661.1
	XM_017003173.1			XP_016858662.1
	XM_017003174.1			XP_016858663.1
	AB021292.1
	AB022317.1			BAA75631.1
	AK075384.1			BAC11584.1
	AK095587.1
	AK291023.1
	AK304358.1
	AK308166.1
	AK312728.1
	AL136552.1			CAB66487.1
	BC018361.1			AAH18361.1
	BC038411.1			AAH38411.1
	KU178531.1
	KU178532.1
	KU178533.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1003960	Chr.2:74630228 - 74769504 on Build GRCh38	Gain	SEMA4F M1AP
nsv1001495	Chr.2:74598036 - 75093218 on Build GRCh38	Gain	LOC105374809 MIR5000 LINC01293 SEMA4F POLE4 LINC01291 TACR1 M1AP HK2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
cell-cell signaling
nervous system development
axon guidance
positive regulation of cell migration
retinal ganglion cell axon guidance
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway

Function(s)

semaphorin receptor binding
neuropilin binding
chemorepellent activity