Hs01537775_cn

• Gene Symbol: SEMA3B
• Assay Reference Genome Location: Chr.3:50275047 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 7869
• Gene Name: semaphorin 3B
• Gene Aliases: LUCA-1, SEMA5, SEMAA, SemA, semaV
• Location: Chr.3:50267558-50277171 on Build GRCh38
• Assay Gene Location: Overlaps Intron 13 - Intron 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA3B	NM_001005914.2			NP_001005914.1
	NM_001290060.1			NP_001276989.1
	NM_001290061.1			NP_001276990.1
	NM_001290062.1			NP_001276991.1
	NM_001290063.1			NP_001276992.1
	NM_004636.3			NP_004627.1
	NR_110697.1
	AB083186.1			BAB88870.1
	AB209322.1			BAD92559.1
	AF217991.1			AAG17234.1
	AK092182.1			BAC03823.1
	AK098329.1	3	1358
	AK293678.1
	BC009113.1			AAH09113.1
	BC013975.2			AAH13975.1
	BC024220.2			AAH24220.1
	BC044602.1			AAH44602.1
	U28369.1			AAD09138.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759148	Chr.3:50161045 - 50333946 on Build GRCh38	Loss	SEMA3B-AS1 LSMEM2 RASSF1 MIR6872 SEMA3B MIR566 MIR5787 NAT6 GNAT1 HYAL2 TUSC2 SEMA3F HYAL1 IFRD2 SLC38A3 HYAL3 GNAI2
nsv523560	Chr.3:50134964 - 50314769 on Build GRCh38	Loss	SEMA3B-AS1 LSMEM2 MIR6872 SEMA3F-AS1 SEMA3B MIR566 MIR5787 NAT6 GNAT1 LOC107986035 SEMA3F HYAL1 IFRD2 SLC38A3 HYAL3 GNAI2
dgv602n27	Chr.3:50140578 - 50287241 on Build GRCh38	Loss	SEMA3B-AS1 LSMEM2 SEMA3F MIR6872 SEMA3F-AS1 SEMA3B MIR566 MIR5787 GNAT1 SLC38A3 LOC107986035 GNAI2
dgv8317n54	Chr.3:50206077 - 50383123 on Build GRCh38	Loss	SEMA3B-AS1 TMEM115 LSMEM2 RASSF1 MIR6872 SEMA3B MIR5787 NAT6 HYAL2 ZMYND10 CYB561D2 TUSC2 NPRL2 HYAL1 IFRD2 SLC38A3 HYAL3 CACNA2D2 GNAI2 RASSF1-AS1
nsv834693	Chr.3:50251400 - 50470533 on Build GRCh38	Loss	SEMA3B-AS1 TMEM115 LSMEM2 RASSF1 MIR6872 SEMA3B NAT6 HYAL2 ZMYND10 CYB561D2 TUSC2 NPRL2 HYAL1 IFRD2 HYAL3 CACNA2D2 GNAI2 RASSF1-AS1
nsv834692	Chr.3:50161052 - 50356033 on Build GRCh38	Loss	SEMA3B-AS1 TMEM115 LSMEM2 RASSF1 MIR6872 SEMA3B MIR566 MIR5787 NAT6 GNAT1 HYAL2 ZMYND10 CYB561D2 TUSC2 SEMA3F NPRL2 HYAL1 IFRD2 SLC38A3 HYAL3 GNAI2 RASSF1-AS1
dgv8316n54	Chr.3:50115923 - 50299991 on Build GRCh38	Loss	SEMA3B-AS1 LSMEM2 MIR6872 SEMA3F-AS1 SEMA3B MIR566 MIR5787 NAT6 GNAT1 LOC107986035 SEMA3F RBM5 HYAL1 IFRD2 SLC38A3 HYAL3 GNAI2
nsv470561	Chr.3:50121341 - 50547568 on Build GRCh38	Loss	SEMA3B-AS1 TMEM115 LSMEM2 RASSF1 SEMA3F-AS1 MIR5787 NAT6 GNAT1 ZMYND10 SEMA3F NPRL2 IFRD2 SLC38A3 CACNA2D2 GNAI2 MIR6872 SEMA3B MIR566 LOC107986035 HYAL2 CYB561D2 TUSC2 HYAL1 HYAL3 RASSF1-AS1
nsv523662	Chr.3:50107518 - 50547568 on Build GRCh38	Loss	SEMA3B-AS1 TMEM115 LSMEM2 RASSF1 SEMA3F-AS1 MIR5787 NAT6 GNAT1 ZMYND10 SEMA3F NPRL2 RBM5 IFRD2 SLC38A3 CACNA2D2 GNAI2 MIR6872 SEMA3B MIR566 LOC107986035 HYAL2 CYB561D2 TUSC2 HYAL1 HYAL3 RASSF1-AS1
nsv590255	Chr.3:50210391 - 50399396 on Build GRCh38	Loss	SEMA3B-AS1 TMEM115 LSMEM2 RASSF1 MIR6872 SEMA3B MIR5787 NAT6 HYAL2 ZMYND10 CYB561D2 TUSC2 NPRL2 HYAL1 IFRD2 SLC38A3 HYAL3 CACNA2D2 GNAI2 RASSF1-AS1
nsv954855	Chr.3:50152468 - 50439169 on Build GRCh38	Deletion	SEMA3B-AS1 TMEM115 LSMEM2 RASSF1 SEMA3F-AS1 MIR5787 NAT6 GNAT1 ZMYND10 SEMA3F NPRL2 IFRD2 SLC38A3 CACNA2D2 GNAI2 MIR6872 SEMA3B MIR566 LOC107986035 HYAL2 CYB561D2 TUSC2 HYAL1 HYAL3 RASSF1-AS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
cell-cell signaling
axon guidance
positive regulation of cell migration
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway

Function(s)

semaphorin receptor binding
neuropilin binding
chemorepellent activity