Hs01412994_cn

• Gene Symbol: NOX1
• Assay Reference Genome Location: Chr.X:100863599 on build GRCh38
• Cytoband: Xq22.1

Target Gene Details

• Entrez Gene ID: 27035
• Gene Name: NADPH oxidase 1
• Gene Aliases: GP91-2, MOX1, NOH-1, NOH1
• Location: Chr.X:100843324-100874345 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NOX1	NM_001271815.1			NP_001258744.1
	NM_007052.4			NP_008983.2
	NM_013955.2			NP_039249.1
	AF166326.1			AAF23232.1
	AF166327.1			AAF23233.1
	AF166328.1			AAF23234.1
	AJ438989.1			CAD27735.1
	AK292201.1
	AK313678.1
	BC075014.2			AAH75014.1
	BC075015.2			AAH75015.1
	BX956931.1
	DQ424904.1			ABD83669.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv7011	Chr.X:100857971 - 100890941 on Build GRCh38	Insertion	XKRX NOX1 HNRNPA1P27

More Information

Additional Information:

• Set Membership: Intragenic, Non-exonic, DGV Variation, Validated

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

angiogenesis
regulation of systemic arterial blood pressure by renin-angiotensin
NADP metabolic process
superoxide metabolic process
inflammatory response
signal transduction
regulation of blood pressure
positive regulation of cell proliferation
positive regulation of vascular endothelial growth factor production
proton transport
cell migration
extracellular matrix organization
regulation of ion transmembrane transport
superoxide anion generation
hydrogen peroxide metabolic process
positive regulation of integrin biosynthetic process
respiratory burst
positive regulation of JNK cascade
positive regulation of smooth muscle cell proliferation
intracellular pH elevation
oxidation-reduction process
cellular response to hyperoxia
oxygen metabolic process
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
cellular stress response to acidic pH

Function(s)

protein binding
superoxide-generating NADPH oxidase activity
voltage-gated proton channel activity
metal ion binding
Rac GTPase binding
NADP binding