Hs01404874_cn

• Gene Symbol: GRIN3B
• Assay Reference Genome Location: Chr.19:1004958 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 116444
• Gene Name: glutamate ionotropic receptor NMDA type subunit 3B
• Gene Aliases: GluN3B, NR3B
• Location: Chr.19:1000419-1009814 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRIN3B	NM_138690.2	3	1476	NP_619635.1
	XM_017026243.1	2	722	XP_016881732.1
	AY507106.1	3	1476	AAS87020.1
	AY507107.1	3	1476	AAS87021.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	CBARP CIRBP-AS1 STK11 KISS1R R3HDM4 RNU6-2 LOC102725180 GRIN3B MIDN CIRBP EFNA2 ATP5D RNU6-9 SBNO2 ABCA7 CNN2 POLR2E ARID3A WDR18 C19orf24 TMEM259 LOC105372235 ARHGAP45 GPX4
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	CIRBP-AS1 KISS1R LOC102725180 GRIN3B ATP5D RNU6-9 ABCA7 CNN2 POLR2E WDR18 C19orf24 ARHGAP45 GPX4 MED16 CBARP STK11 R3HDM4 RNU6-2 MIDN CIRBP EFNA2 SBNO2 ARID3A TMEM259 LOC105372235
nsv578188	Chr.19:923744 - 1059005 on Build GRCh38	Loss	ABCA7 CNN2 ARID3A WDR18 RNU6-2 GRIN3B TMEM259 LOC105372235
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	ABCA7 CNN2 POLR2E ARID3A WDR18 RNU6-2 GRIN3B TMEM259 LOC105372235 ARHGAP45 GPX4 SBNO2
esv2758743	Chr.19:951641 - 1544934 on Build GRCh38	Gain+Loss	RPS15 CIRBP-AS1 REEP6 LOC102725180 GRIN3B ATP5D ABCA7 CNN2 POLR2E WDR18 C19orf24 NDUFS7 ARHGAP45 GPX4 MUM1 APC2 C19orf25 CBARP STK11 RNU6-2 MIDN ADAMTSL5 CIRBP EFNA2 SBNO2 ARID3A PCSK4 DAZAP1 TMEM259 LOC105372235 GAMT PLK5
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	PRTN3 KISS1R MIR4745 PALM GRIN3B C2CD4C SHC2 RNF126 RNU6-9 ABCA7 MADCAM1 CNN2 POLR2E WDR18 FSTL3 PLPPR3 ARHGAP45 GPX4 FGF22 HCN2 ODF3L2 MED16 ELANE MISP CFD GZMM R3HDM4 RNU6-2 TPGS1 CDC34 AZU1 PRSS57 ARID3A LOC101928450 POLRMT PTBP1 MIR3187 TMEM259 THEG LOC105372235 BSG
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	PRTN3 KISS1R MIR4745 PALM GRIN3B C2CD4C SHC2 RNF126 RNU6-9 MADCAM1 WDR18 FSTL3 PLPPR3 FGF22 HCN2 ODF3L2 MED16 ELANE MISP CFD GZMM R3HDM4 TPGS1 CDC34 AZU1 PRSS57 ARID3A LOC101928450 POLRMT PTBP1 MIR3187 LOC105372235 BSG

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

ionotropic glutamate receptor signaling pathway
protein insertion into membrane
regulation of calcium ion transport
calcium ion transmembrane transport

Function(s)

NMDA glutamate receptor activity
extracellular-glutamate-gated ion channel activity
cation channel activity
calcium channel activity
glycine binding
neurotransmitter receptor activity
neurotransmitter binding