Hs01351690_cn

• Gene Symbol: KLRG1
• Assay Reference Genome Location: Chr.12:9166070 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10219
• Gene Name: killer cell lectin like receptor G1
• Gene Aliases: 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
• Location: Chr.12:8989079-9255692 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRG1	XM_017018685.1			XP_016874174.1

Target Gene Details

• Entrez Gene ID: 5858
• Gene Name: PZP, alpha-2-macroglobulin like
• Gene Aliases: CPAMD6
• Location: Chr.12:9140730-9208370 on Build GRCh38
• Assay Gene Location: Overlaps Intron 17 - Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PZP	NM_002864.2			NP_002855.2
	XM_011520804.2			XP_011519106.1
	XM_011520805.2			XP_011519107.1
	XM_011520806.1			XP_011519108.1
	XM_011520807.2			XP_011519109.1
	XM_017019763.1			XP_016875252.1
	XM_017019764.1			XP_016875253.1
	XM_017019765.1			XP_016875254.1
	XM_017019766.1			XP_016875255.1
	XM_017019767.1			XP_016875256.1
	AK302259.1
	AK308724.1
	AK313639.1
	BC111756.1			AAI11757.1
	DB040351.1
	X54380.1			CAA38255.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv523958	Chr.12:9150844 - 9396476 on Build GRCh38	Loss	KLRG1 LOC105369649 PZP LOC642846 LOC101928030 MIR1244-3 LOC101930452 LINC00987 A2MP1
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	KLRF1 AICDA MFAP5 CLEC6A CLEC2A A2ML1 LOC400002 OVOS LOC105369728 CLEC4D MIR1244-3 DDX12P CLEC4E A2M PHC1 KLRG1 LOC105369649 KLRF2 PZP CLEC2D LOC105376678 CLEC2B LOC101930452 RIMKLB LOC374443 A2M-AS1 KLRB1 A2MP1 M6PR LOC728715 LOC642846 LINC00612 CD69 LOC100506159 CLEC12A LOC101928030 CLECL1 LINC00987
nsv527404	Chr.12:9098005 - 9282648 on Build GRCh38	Gain	KLRG1 PZP MIR1244-3 LINC00987 A2M A2MP1
nsv557355	Chr.12:9157399 - 9376419 on Build GRCh38	Gain	KLRG1 LOC105369649 PZP LOC642846 LOC101928030 MIR1244-3 LOC101930452 LINC00987 A2MP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor, protease inhibitor

Gene Ontology Categories:

Process(es)

inflammatory response
cellular defense response
cell surface receptor signaling pathway
innate immune response
female pregnancy
negative regulation of endopeptidase activity

Function(s)

receptor activity
protein binding
carbohydrate binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity