Hs01186166_cn

• Gene Symbol: KLRG1
• Assay Reference Genome Location: Chr.12:9152848 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10219
• Gene Name: killer cell lectin like receptor G1
• Gene Aliases: 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
• Location: Chr.12:8989079-9255692 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRG1	XM_017018685.1			XP_016874174.1

Target Gene Details

• Entrez Gene ID: 5858
• Gene Name: PZP, alpha-2-macroglobulin like
• Gene Aliases: CPAMD6
• Location: Chr.12:9140730-9208370 on Build GRCh38
• Assay Gene Location: Overlaps Intron 31 - Exon 31

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PZP	NM_002864.2			NP_002855.2
	XM_011520804.2			XP_011519106.1
	XM_011520805.2			XP_011519107.1
	XM_017019763.1			XP_016875252.1
	XM_017019764.1			XP_016875253.1
	XM_017019765.1			XP_016875254.1
	XM_017019766.1			XP_016875255.1
	AK313639.1
	BC111756.1			AAI11757.1
	X54380.1			CAA38255.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv523958	Chr.12:9150844 - 9396476 on Build GRCh38	Loss	LOC101928030 LOC642846 LOC101930452 LINC00987 LOC105369649 MIR1244-3 PZP KLRG1 A2MP1
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	LOC728715 LOC400002 LOC101928030 CLEC12A KLRF1 LOC101930452 RIMKLB OVOS CLEC2B PHC1 LOC374443 AICDA MFAP5 A2M-AS1 CLEC4E LOC105376678 LINC00987 LOC105369649 MIR1244-3 LINC00612 KLRG1 KLRF2 M6PR CLEC6A LOC105369728 A2ML1 CLECL1 A2MP1 KLRB1 CD69 A2M LOC642846 DDX12P CLEC2D LOC100506159 PZP CLEC2A CLEC4D
nsv527404	Chr.12:9098005 - 9282648 on Build GRCh38	Gain	A2M LINC00987 MIR1244-3 PZP KLRG1 A2MP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor, protease inhibitor

Gene Ontology Categories:

Process(es)

inflammatory response
cellular defense response
cell surface receptor signaling pathway
innate immune response
female pregnancy
negative regulation of endopeptidase activity

Function(s)

receptor activity
protein binding
carbohydrate binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity