Hs00907371_cn

• Gene Symbol: ISLR2
• Assay Reference Genome Location: Chr.15:74135274 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 57611
• Gene Name: immunoglobulin superfamily containing leucine rich repeat 2
• Gene Aliases: LINX
• Location: Chr.15:74128203-74141826 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ISLR2	NM_001130136.1	4	3289	NP_001123608.1
	NM_001130137.1	4	3025	NP_001123609.1
	NM_001130138.1	4	2733	NP_001123610.1
	NM_020851.2	3	2858	NP_065902.1
	XM_011521840.2	4	3128	XP_011520142.1
	XM_011521841.1	4	2811	XP_011520143.1
	XM_017022446.1			XP_016877935.1
	AB040898.2	4	3289
	AK092297.1	3	2684
	AK092302.1
	AK096602.1	2	2636
	AY358316.1	3	2656	AAQ88682.1
	BC114551.1	3	1372	AAI14552.1
	BC152429.1	4	3289

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833053	Chr.15:74067815 - 74262799 on Build GRCh38	Loss	STRA6 ISLR2 LOC283731 CCDC33 GOLGA6A LOC732265 ISLR
nsv1050884	Chr.15:74102642 - 74197072 on Build GRCh38	Gain	STRA6 ISLR2 LOC283731 ISLR
nsv469619	Chr.15:73999518 - 74173980 on Build GRCh38	Loss	ISLR2 LOC283731 GOLGA6A PML LOC732265 ISLR
nsv827385	Chr.15:74127198 - 74136960 on Build GRCh38	Gain	ISLR2 LOC283731
nsv951993	Chr.15:74124460 - 74137359 on Build GRCh38	Deletion	ISLR2 LOC283731
esv2760040	Chr.15:73922773 - 74172575 on Build GRCh38	Gain+Loss	LOXL1-AS1 ISLR2 LOC283731 GOLGA6A LOXL1 PML LOC732265 STOML1
nsv1047564	Chr.15:74116495 - 74165840 on Build GRCh38	Gain	ISLR2 LOC283731
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	STRA6 C15orf39 CYP1A2 GOLGA6A FAM219B RPP25 LOC732265 MIR4513 LMAN1L C15orf59-AS1 GOLGA6C UBL7-AS1 CYP1A1 CSK HIGD2B REC114 EDC3 ULK3 LOC107984728 HCN4 UBL7 CYP11A1 LOXL1-AS1 PPCDC BBS4 LOC105376731 CD276 STOML1 LOC102723750 LOXL1 SCAMP5 PML SCAMP2 NEO1 CLK3 LOC283731 CCDC33 TBC1D21 NPTN-IT1 COX5A NPTN ADPGK-AS1 MIR6882 LOC101929333 ISLR ARID3B MIR6881 ISLR2 MPI ADPGK LOC729739 CPLX3 C15orf59 SEMA7A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin superfamily cell adhesion molecule

Gene Ontology Categories:

Process(es)

positive regulation of axon extension