Hs00882562_cn

• Gene Symbol: KLRG1
• Assay Reference Genome Location: Chr.12:9161087 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10219
• Gene Name: killer cell lectin like receptor G1
• Gene Aliases: 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
• Location: Chr.12:8989079-9255692 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRG1	XM_017018685.1			XP_016874174.1

Target Gene Details

• Entrez Gene ID: 5858
• Gene Name: PZP, alpha-2-macroglobulin like
• Gene Aliases: CPAMD6
• Location: Chr.12:9140730-9208370 on Build GRCh38
• Assay Gene Location: Overlaps Intron 22 - Exon 23

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PZP	NM_002864.2			NP_002855.2
	XM_011520804.2			XP_011519106.1
	XM_011520805.2			XP_011519107.1
	XM_011520806.1			XP_011519108.1
	XM_017019763.1			XP_016875252.1
	XM_017019764.1			XP_016875253.1
	XM_017019765.1			XP_016875254.1
	XM_017019766.1			XP_016875255.1
	AK302259.1
	AK308724.1
	AK313639.1
	BC111756.1			AAI11757.1
	X54380.1			CAA38255.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv523958	Chr.12:9150844 - 9396476 on Build GRCh38	Loss	KLRG1 LOC105369649 LINC00987 LOC101928030 LOC642846 A2MP1 MIR1244-3 PZP LOC101930452
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	LOC400002 LOC642846 LOC100506159 MIR1244-3 PZP KLRG1 M6PR LINC00987 LOC101928030 A2M-AS1 LINC00612 LOC374443 CLEC12A A2ML1 CLECL1 CLEC2A KLRF1 AICDA LOC105376678 DDX12P CD69 OVOS CLEC2B CLEC4D PHC1 MFAP5 LOC101930452 CLEC2D LOC728715 CLEC4E LOC105369649 A2MP1 LOC105369728 CLEC6A RIMKLB KLRB1 KLRF2 A2M
nsv527404	Chr.12:9098005 - 9282648 on Build GRCh38	Gain	KLRG1 LINC00987 A2MP1 MIR1244-3 PZP A2M
nsv557355	Chr.12:9157399 - 9376419 on Build GRCh38	Gain	KLRG1 LOC105369649 LINC00987 LOC101928030 LOC642846 A2MP1 MIR1244-3 PZP LOC101930452

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor, protease inhibitor

Gene Ontology Categories:

Process(es)

inflammatory response
cellular defense response
cell surface receptor signaling pathway
innate immune response
female pregnancy
negative regulation of endopeptidase activity

Function(s)

receptor activity
protein binding
carbohydrate binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity